Nav1.8-IN-14
Based on 1 Customer Validation
Nav1.8-IN-14 (compound 20) is a potent and selective Nav1.8 inhibitor. Nav1.8-IN-14 can be used in the study of pain-related diseases.
For research use only. We do not sell to patients.
- Purity: 99.83%
- CAS No.: 2417373-18-1
- Formula: C18H17F5N4O3S
- Molecular Weight:464.41
-
Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
-
CAS No. 2417373-18-1
-
Appearance Solid
-
Molecular Weight 464.41
-
Formula C18H17F5N4O3S
-
Color White to off-white
-
SMILES
FC(F)(F)C1=CN=C(N(CC2)CCC2(F)F)C(C(NC3=CC(S(N)(=O)=O)=CC=C3)=O)=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (215.33 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (270 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1533 mL | 10.7663 mL | 21.5327 mL | 53.8317 mL |
| 5 mM | 0.4307 mL | 2.1533 mL | 4.3065 mL | 10.7663 mL | |
| 10 mM | 0.2153 mL | 1.0766 mL | 2.1533 mL | 5.3832 mL | |
| 15 mM | 0.1436 mL | 0.7178 mL | 1.4355 mL | 3.5888 mL | |
| 20 mM | 0.1077 mL | 0.5383 mL | 1.0766 mL | 2.6916 mL | |
| 25 mM | 0.0861 mL | 0.4307 mL | 0.8613 mL | 2.1533 mL | |
| 30 mM | 0.0718 mL | 0.3589 mL | 0.7178 mL | 1.7944 mL | |
| 40 mM | 0.0538 mL | 0.2692 mL | 0.5383 mL | 1.3458 mL | |
| 50 mM | 0.0431 mL | 0.2153 mL | 0.4307 mL | 1.0766 mL | |
| 60 mM | 0.0359 mL | 0.1794 mL | 0.3589 mL | 0.8972 mL | |
| 80 mM | 0.0269 mL | 0.1346 mL | 0.2692 mL | 0.6729 mL | |
| 100 mM | 0.0215 mL | 0.1077 mL | 0.2153 mL | 0.5383 mL |