Nav1.8-IN-4
Based on 1 Customer Validation
Nav1.8-IN-4 (compound 9a) is a Nav1.8 channel inhibitor (IC50=0.014 μM). Nav1.8-IN-4 can be used for research on pain-related diseases.
For research use only. We do not sell to patients.
- Purity: 99.78%
- CAS No.: 1620846-16-3
- Formula: C20H14F4N2O3
- Molecular Weight:406.33
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50=0.014 μM (Nav1.8)[1].
Chemical Information
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CAS No. 1620846-16-3
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Appearance Solid
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Molecular Weight 406.33
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Formula C20H14F4N2O3
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Color White to off-white
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SMILES
O=C1C=C(NC(C2=CC=C(C(F)(F)F)C=C2OC3=CC=C(C=C3C)F)=O)C=CN1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 116.67 mg/mL (287.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4611 mL | 12.3053 mL | 24.6105 mL | 61.5263 mL |
| 5 mM | 0.4922 mL | 2.4611 mL | 4.9221 mL | 12.3053 mL | |
| 10 mM | 0.2461 mL | 1.2305 mL | 2.4611 mL | 6.1526 mL | |
| 15 mM | 0.1641 mL | 0.8204 mL | 1.6407 mL | 4.1018 mL | |
| 20 mM | 0.1231 mL | 0.6153 mL | 1.2305 mL | 3.0763 mL | |
| 25 mM | 0.0984 mL | 0.4922 mL | 0.9844 mL | 2.4611 mL | |
| 30 mM | 0.0820 mL | 0.4102 mL | 0.8204 mL | 2.0509 mL | |
| 40 mM | 0.0615 mL | 0.3076 mL | 0.6153 mL | 1.5382 mL | |
| 50 mM | 0.0492 mL | 0.2461 mL | 0.4922 mL | 1.2305 mL | |
| 60 mM | 0.0410 mL | 0.2051 mL | 0.4102 mL | 1.0254 mL | |
| 80 mM | 0.0308 mL | 0.1538 mL | 0.3076 mL | 0.7691 mL | |
| 100 mM | 0.0246 mL | 0.1231 mL | 0.2461 mL | 0.6153 mL |
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