Neutrophil elastase inhibitor 6
Neutrophil elastase inhibitor 6 is a dual inhibitor of human neutrophil elastase (HNE) and proteinase 3 (PR3), with high selectivity for cathepsin G. Neutrophil elastase inhibitor 6 can be used in the research of chronic neutrophilic inflammatory diseases.
For research use only. We do not sell to patients.
- Formula: C38H48N3O12PS3
- Molecular Weight:865.97
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Neutrophil elastase inhibitor 6 (Compound 113) potently inhibits human neutrophil elastase with a kinact/KI of 4,236,800 M-1s-1, shows even greater potency against proteinase 3, and is highly selective for these two proteases over cathepsin G[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 865.97
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Formula C38H48N3O12PS3
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SMILES
O=C(O)COC1=CC=C(OCC(N[C@@H](CCS(=O)(C)=O)C(N2[C@H](C(N[C@H](P(OC3=CC=C(SC)C=C3)(OC4=CC=C(SC)C=C4)=O)C(C)C)=O)CCC2)=O)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Neutrophil elastase inhibitor 6 Related Classifications
HY-163411 Related Classifications
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