NH2-MPAA-NODA TFA
NH2-MPAA-NODA TFA is a nitroveratryl-based photocleavable linker, it has a NODA motif and a methyl phenyl acetic acid (MPAA) backbone. NH2-MPAA-NODA can be used as a radiolabel by labeling with 18F-fluoride.
For research use only. We do not sell to patients.
- Formula: C23H34F3N5O7
- Molecular Weight:549.54
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
NH2-MPAA-NODA TFA contains the 1,4,7-triazacyclononane-1,4-diacetate (NODA) motif with a methyl phenyl acetic acid (MPAA) backbone, and it has enough ability to form stable Al18F-chelates. NH2-MPAA-NODA can be conjugated to some inhibitors/antagonists labeled with 18F for PET imaging of targeting tumors. It also can be used as a radiolabel of peptides[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 549.54
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Formula C23H34F3N5O7
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SMILES
O=C(NCCN)CC1=CC=C(C=C1)CN2CCN(CC(O)=O)CCN(CC(O)=O)CC2.OC(C(F)(F)F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 100 mg/mL (181.97 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| H2O | 1 mM | 1.8197 mL | 9.0985 mL | 18.1970 mL | 45.4926 mL |
| 5 mM | 0.3639 mL | 1.8197 mL | 3.6394 mL | 9.0985 mL | |
| 10 mM | 0.1820 mL | 0.9099 mL | 1.8197 mL | 4.5493 mL | |
| 15 mM | 0.1213 mL | 0.6066 mL | 1.2131 mL | 3.0328 mL | |
| 20 mM | 0.0910 mL | 0.4549 mL | 0.9099 mL | 2.2746 mL | |
| 25 mM | 0.0728 mL | 0.3639 mL | 0.7279 mL | 1.8197 mL | |
| 30 mM | 0.0607 mL | 0.3033 mL | 0.6066 mL | 1.5164 mL | |
| 40 mM | 0.0455 mL | 0.2275 mL | 0.4549 mL | 1.1373 mL | |
| 50 mM | 0.0364 mL | 0.1820 mL | 0.3639 mL | 0.9099 mL | |
| 60 mM | 0.0303 mL | 0.1516 mL | 0.3033 mL | 0.7582 mL | |
| 80 mM | 0.0227 mL | 0.1137 mL | 0.2275 mL | 0.5687 mL | |
| 100 mM | 0.0182 mL | 0.0910 mL | 0.1820 mL | 0.4549 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
NH2-MPAA-NODA TFA Related Classifications
HY-135859A Related Classifications
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