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Notoginsenoside Fc 

Cat. No.: HY-N2531
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Notoginsenoside Fc, a protopanaxadiol- (PPD-) type saponin isolated from the leaves of Panax notoginseng, effectively counteracts platelet aggregation. Notoginsenoside Fc can accelerate reendothelialization following vascular injury in diabetic rats by promoting autophagy.

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Notoginsenoside Fc Chemical Structure

Notoginsenoside Fc Chemical Structure

CAS No. : 88122-52-5

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Description

Notoginsenoside Fc, a protopanaxadiol- (PPD-) type saponin isolated from the leaves of Panax notoginseng, effectively counteracts platelet aggregation. Notoginsenoside Fc can accelerate reendothelialization following vascular injury in diabetic rats by promoting autophagy[1].

In Vitro

Notoginsenoside Fc (20 μM; for 24 h) markedly upregulates the expression of LC3B and Beclin 1 and downregulated that of p62 in RAOECs[1].

In Vivo

Notoginsenoside Fc (3.5 mg/kg/day) accelerates reendothelialization and alleviates excessive neointimal formation following carotid artery injury in diabetic Sprague-Dawley rats (200±20 g) in vivo[1].

Molecular Weight

1211.38

Formula

C₅₈H₉₈O₂₆

CAS No.

88122-52-5

SMILES

C[[email protected]]12[[email protected]]3([[email protected]@](C[[email protected]@H](O)[[email protected]]1([H])[[email protected]]([[email protected]@](CC/C=C(C)/C)(C)O[[email protected]@H]4O[[email protected]@H]([[email protected]@H](O)[[email protected]](O)[[email protected]]4O)CO[[email protected]]5[[email protected]@H]([[email protected]]([[email protected]](O)CO5)O)O)([H])CC2)([H])[[email protected]@]6([[email protected]@](C(C)([[email protected]@H](O[[email protected]@]7([H])[[email protected]@H]([[email protected]]([[email protected]](O)[[email protected]@H](CO)O7)O)O[[email protected]@]8([H])[[email protected]@H]([[email protected]]([[email protected]](O)[[email protected]@H](CO)O8)O)O[[email protected]@]9([H])[[email protected]@H]([[email protected]]([[email protected]](O)CO9)O)O)CC6)C)([H])CC3)C)C

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Keywords:

Notoginsenoside FcAutophagyProtopanaxadiolplateletaggregationreendothelializationvascularinjurydiabeticInhibitorinhibitorinhibit

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Notoginsenoside Fc
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