Octyl decyldimethyl ammonium chloride
Octyl decyldimethyl ammonium chloride, a quaternary ammonium salt, is an antibacterial agent. Octyl decyldimethyl ammonium chloride disrupts cell membranes, leading to cytotoxicity. Octyl decyldimethyl ammonium chloride has risk of skin irritation and increases pro-inflammatory IL-1α secretion.
For research use only. We do not sell to patients.
- CAS No.: 32426-11-2
- Formula: C20H44ClN
- Molecular Weight:334.03
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
IL-1α |
In Vitro
Octyl decyldimethyl ammonium chloride (present in QAC#1) (0.25-60 min) shows antibacterial activity Staphylococcus aureus[1].
Octyl decyldimethyl ammonium chloride (present in QAC#1) (1-4 h) induces cytotoxicity in L929 murine fibroblasts[1].
Octyl decyldimethyl ammonium chloride (present in QAC#1) (15 min-48 h) induces a significant decrease in reconstructed human epidermis viability to 56% and increases pro-inflammatory IL-1α secretion[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:C57BL/6N (female, 10 weeks old)[1]
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Dosage:1-5% w/w (as part of QAC#1 solution)
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Administration:topical; single exposure; 4 h
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Result:Induced erythema and edema scores ranging from 0 to 2 across 24, 48, and 72 hours post-treatment.
Produced total irritation scores ranging from 0 to 4, with a mean of 1.7.
Caused focal epidermal necrosis, small scab formation, slightly disorganized dermis with cell infiltration, and significant epidermal thickening in 4 out of 5 mice.
Chemical Information
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CAS No. 32426-11-2
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Molecular Weight 334.03
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Formula C20H44ClN
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SMILES
[Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Octyl decyldimethyl ammonium chloride Related Classifications
HY-W353842 Related Classifications
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