Adenine Nucleotide

Adenosine 5'-O-thiomonophosphate dilithium is a compound that inhibits phosphohydrolase activity and can also serve as a substrate for 5'-nucleotidase.

2'-Deoxyadenosine 3':5'-cyclic monophosphate (sodium) is a kind of biochemical reagent.

7-Deazaadenosine 5'-phosphate (Tubercidin 5'-phosphate; 7-Deaza-AMP) is a potential substrate or competitive inhibitor of enzymes that interact with 5′-adenylic acid monophosphate. As a nucleotide derivative, 7-Deazaadenosine 5'-phosphate can regulate cellular functions by affecting intracellular signaling pathways, especially in signaling involving AMP.

Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca²⁺ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group.

1,N6-Ethenoadenosine 5'-monophosphate (1,N6-Etheno-AMP) sodium is a highly fluorescent analog of adenosine 5'-monophosphate (AMP). 1,N6-Ethenoadenosine 5'-monophosphate sodium is a powerful probe for systems involving adenosine 5'-monophosphate and can be detected at low concentration. 1,N6-Ethenoadenosine 5'-monophosphate sodium has long wavelength of excitation (250-300 nm), and emission at 415 nm.

Diadenosine pentaphosphate (Ap5A; P1,P5-Di(adenosine-5'-)pentaphosphate) pentalithium is an endogenous generated diadenosine polyphosphate, possessing the dual identities of intracellular alarm signal and extracellular signaling molecule. Diadenosine pentaphosphate regulates calcium signaling in the nervous, cardiac and peripheral sensory systems by activating P2X1/P2X3/P2Y receptor and RyR2 channels (EC₅₀ = 140 μM). Diadenosine pentaphosphate can be used in studies related to intracellular calcium release channels, cardiovascular diseases and nociception (pain).

Adenosine 2',3'-cyclic phosphate is a naturally occurring adenosine cyclic phosphate derivative. Adenosine 2',3'-cyclic phosphate is used to detect the activity of 2',3'-cyclic nucleotide 3'-phosphodiesterase.

3'-O-(2-Nitrobenzyl)-dATP is a reversible and photolabile DNA synthesis terminator. 3'-O-(2-Nitrobenzyl)-dATP incorporates into growing DNA strands to terminate synthesis in a base-specific manner. 3'-O-(2-Nitrobenzyl)-dATP undergoes efficient photolytic removal of its 3'-protecting group upon UV exposure to enable reinitiation of DNA synthesis. 3'-O-(2-Nitrobenzyl)-dATP supports development of the Base Addition Sequencing Scheme (BASS) via a complete stop-start DNA synthesis cycle.

3'-Amino-2',3'-dideoxy-ATP is a modified nucleotide. 3'-Amino-2',3'-dideoxy-ATP can serve as a potent chain terminator for various DNA sequencing methods, including radioactive and fluorescent sequencing, and is compatible with multiple sequencing enzymes.

2'-F-ADP is a nucleotide analog that can be used in the synthesis of oligonucleotides.

2'-F-AMP is a nucleotide analog that can be used in the synthesis of oligonucleotides.

LNA-AMP is a nucleotide analog that can be used in the synthesis of oligonucleotides.

LNA-ATP is a nucleotide analog that can be used in the synthesis of oligonucleotides.

2′-OMe-ADP is a nucleotide analog that can be used in the synthesis of oligonucleotides.

2′-O-MOE-AMP is a nucleotide analog that can be used in the synthesis of oligonucleotides.

2'-Deoxy-3'-O-valeryladenosine-5'-O-triphosphate (triethylammonium) is a derivative of 2'-Deoxyadenosine-5'-triphosphate (HY-136648). 2'-Deoxy-3'-O-valeryladenosine-5'-O-triphosphate (triethylammonium) is used in cells for DNA synthesis, sequencing and labeling studies.

2'-Deoxy-3'-O-pivaloyladenosine-5'-O-triphosphate (3'-O-Pivaloyl dATP) triethylammonium is a derivative of 2'-Deoxyadenosine-5'-triphosphate trisodium (HY-136648A).

2'-Deoxy-3'-O-monosuccinyladenosine-5'-O-triphosphate (3'-O-monosuccinyl dATP) triethylammonium is a derivative of the purine nucleotide 2'-deoxyadenosine-5'-O-triphosphate.

2'-Deoxy-3'-O-isovaleryladenosine-5'-O-triphosphate (2'-Deoxy-3'-IVal-dATP) triethylammonium is a derivative of the purine nucleotide 2'-deoxyadenosine-5'-O-triphosphate (dATP; HY-136648).

3′-Deoxyadenosine 5′-triphosphate trisodiumCan be used for nucleic acid synthesis.