Chelators
Chelators refer to a class of compounds capable of forming complexes with metal ions. They contain two or more ligands that react with metal ions to form stable chelates. Typically, chelators possess multiple functional groups, such as quaternary ammonium and amino groups, which can encapsulate metal ions within the molecule. This encapsulation reduces the catalytic performance of metal ions, thereby mitigating their influence on reactions.
Chelators are widely used in the fields of pharmaceutical preparations, cosmetics and food to regulate pH values and enhance stability.
- Formula: C24H37Cl2N5O8
- Molecular Weight: 594.49
p-NH?-Bn-PCTA (hydrochloride)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DPTA derivative used for tumor pre-targeting. p-NH?-Bn-PCTA (hydrochloride) can be used for conjugation of peptides and radionuclides.
- Formula: C26H32F9N5O17
- Molecular Weight: 857.54
Maleimido-mono-amide-DTPA (TFA)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DPTA derivative used for tumor pre-targeting. Maleimido-mono-amide-DTPA (TFA) can be used for conjugation of peptides and radionuclides.
- Formula: C12H24Cl3N3O6
- Molecular Weight: 412.69
NOTA (trihydrochloride)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NOTA (trihydrochloride) can be used for conjugation of peptides and radionuclides.
- Formula: C24H42N4O5
- Molecular Weight: 466.61
NO2A-Butyne-bis(t-Butyl ester)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Butyne-bis(t-Butyl ester) can be used for conjugation of peptides and radionuclides.
- Formula: C15H25N5O2
- Molecular Weight: 307.39
p-NO2-Bn-Cyclenis a bifunctional chelator (Bifunctional Chelator; BFC), which is a derivative of the macrocyclic ligand dodecane backbone Cyclen. p-NO2-Bn-Cyclen can be used for conjugation of peptides and radionuclides.
- Formula: C18H35N3O4
- Molecular Weight: 357.49
NO2A-(t-Bu ester)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-(t-Bu ester) can be used for conjugation of peptides and radionuclides.
- Formula: C12H26N4
- Molecular Weight: 226.36
CB-Cyclamis a bifunctional chelator (Bifunctional Chelator; BFC), which is a main chain Cyclen derivative of the macrocyclic ligand tetradecane. CB-Cyclam can be used for conjugation of peptides and radionuclides.
- Formula: C9H24N3O9P3
- Molecular Weight: 411.22
NOTPis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NOTP can be used for conjugation of peptides and radionuclides.
- Formula: C24H32N4O4
- Molecular Weight: 440.54
Bis-Cbz-cyclen is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical.
- Formula: C14H39Cl5N8
- Molecular Weight: 496.78
Diamsar hydrochloride is a bifunctional chelator.
- Formula: C12H18N2O5S
- Molecular Weight: 302.35
Nitroso-PSAP is a sensitive and specific chromogenic reagent for iron (Fe2+), which is used for the colorimetric determination of iron in blood after mineralization with periodic acid. TNitroso-PSAP chelates with iron (Fe2+) to produce a green complex (λmax=756 nm, Epsilon = 4.5 x 10 < sup > 4 < / sup > dm < sup > 3 < / sup > mol < sup > 1 < / sup > cm < sup > 1 < / sup >).
- Formula: C56H42BF48NaO11
- Molecular Weight: 1836.65
HFPB (Compound 2) is a type of cation exchanger with high lipophilicity and acid resistivity, which can be used in membrane electrode research.
- Formula: C17H23N5Na2O8S
- Molecular Weight: 503.44
Nitro-PAPS disodium dihydrate is a highly sensitive colometric reagent for Fe(II) detection with a maximal absorption wavelength of 592 nm. Nitro-PAPS disodium dihydrate is suitable for the determination of Fe(II) in serum and also be used to determine micro molar levels of Cu, Zn, Ni, Co and V.
- Formula: C24H32O4
- Molecular Weight: 384.51
Dibenzyl-14-crown-4 (6,6-Dibenzyl-1,4,8,11-tetraoxacyclotetradecane) is a crown ether derivate, which serves as neutral carrier in PVC ion-selective electrode, improves the Li+ selectivity against Na+ and K+.
- Formula: C10H12FeN2NaO8.xH2O
EDTA iron sodium hydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
- Formula: C10H17K3N2O10
- Molecular Weight: 442.54
EDTA dihydrate tripotassium (Ethylenediaminetetraacetic acid dihydrate tripotassium) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). EDTA dihydrate tripotassium has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. EDTA dihydrate tripotassium decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. EDTA dihydrate tripotassium can alleviate the liver fibrosis. EDTA dihydrate tripotassium can be used for coronary artery disease and neural system disease research.
- Formula: C10H12K2MgN2O8
- Molecular Weight: 390.71
EDTA dipotassium magnesium (Ethylenediaminetetraacetic acid dipotassium magnesium) is a biochemical reagent that can be used in studies related to organic synthesis.
- Formula: C19H24BrN3O9
- Molecular Weight: 518.31
(Rac)-EDTA-bromoacetamidophenylmethyl is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
- Formula: C19H24BrN3O9
- Molecular Weight: 518.31
EDTA-p-Bromoacetamido benzyl ((S)-1-(p-Bromoacetamidobenzyl)ethylenediaminetetraacetic acid) is a compound of EDTA and phenylbromoacetamide that can be coupled to antibodies.
