2. GPCR/G Protein MAPK/ERK Pathway
  3. Ras
  4. pan-KRAS-IN-9

pan-KRAS-IN-9 (Compound 52) is an inhibitor for in human tumor mutated genes KRAS, which inhibits proliferation of KRAS mutated cells AsPC-1 (G12D mutant) and SW480 (G12V mutant) with IC50 of 0.24 and 0.30 nM, respectively.

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pan-KRAS-IN-9

pan-KRAS-IN-9 Estructura química

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pan-KRAS-IN-9 Related Antibodies

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Descripciòn

pan-KRAS-IN-9 (Compound 52) is an inhibitor for in human tumor mutated genes KRAS, which inhibits proliferation of KRAS mutated cells AsPC-1 (G12D mutant) and SW480 (G12V mutant) with IC50 of 0.24 and 0.30 nM, respectively[1].

Peso molecular

863.12

Fòrmula

C48H62N8O5S
SMILES

CO[C@@H](C)C(N=C1)=[C@@]([C@@]2=C(CC(C)(C)COC3=O)C4=CC(C5=CSC(C[C@H](NC([C@H]6[C@H](C)[C@@H]6C)=O)C(N7CCC[C@@H]3N7)=O)=N5)=CC=C4N2CC)C=C1C#CCN8CCN(C)CC8
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pan-KRAS-IN-9 Related Classifications

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Keywords:

pan-KRAS-IN-9Raspancreatic cancercolorectal adenocarcinomasAsPC-1SW480Inhibitorinhibitorinhibit

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pan-KRAS-IN-9
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HY-162442
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