PD-1/PD-L1-IN-49
PD-1/PD-L1-IN-49 (compound 1c) is a potent inhibitor of PD-1/PD-L1, with the IC50 of 77 nM. PD-1/PD-L1-IN-49 activates Jurkat T cells, reflecting successful blockade of the PD-1/PD-L1 immune checkpoint.
For research use only. We do not sell to patients.
- Formula: C27H32N4O5
- Molecular Weight:492.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 492.57
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Formula C27H32N4O5
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SMILES
CC1=C(C2=CC3=C(C=C2)N(C)CCO3)C=CC=C1NC(C4=NC=C(CNC(CO)(CO)CO)C=C4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)