country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-183300

Copy Link Print Information

PD-L1-IN-10

PD-L1-IN-10 is a PD-L1 inhibitor with a K_i value of 5.7 μM. PD-L1-IN-10 inhibits PD-1/PD-L1 protein-protein interaction. PD-L1-IN-10 is used in cancer-related research.

For research use only. We do not sell to patients.

Formula: C₂₈H₃₁FN₁₀O₆
Molecular Weight:622.61

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

PD-L1-IN-10 Chemical Structure

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

PD-L1-IN-10 is a PD-L1 inhibitor with a K_i value of 5.7 μM. PD-L1-IN-10 inhibits PD-1/PD-L1 protein-protein interaction. PD-L1-IN-10 is used in cancer-related research^[1].

In Vitro

PD-L1-IN-10 (Compound 2c) inhibits the PD-1/PD-L1 protein-protein interaction^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 622.61
Formula C₂₈H₃₁FN₁₀O₆
SMILES

O=C(N1CCC(CC1)NC2=CNC(N(C2=O)CC3=NC(C4=CC(C(N5CCOCC5)=O)=NC=C4)=NO3)=O)CCC6=NC(F)=CN6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Ohira S, et al. AI-assisted transformation of PD-L1 inhibitory peptides into small molecules using amino acid mapping descriptor and activity improvement through structure-based drug design. Bioorg Med Chem Lett. 2026;137:130655. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote