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DTPA  (Synonyms: ジエチレントリアミン五酢酸; Pentetic acid; Diethylenetriaminepentaacetic acid)

製品番号: HY-B1335 純度: 99.80%
COA 取扱説明書 Technical Support

Pentetic acid (Diethylenetriaminepentaacetic acid) is an orally active compound with biodegradability used to construct magnetic adsorbent, which can simultaneously remove heavy metal and dye from complex wastewater. Pentetic acid can form strong metal complexes, which prevents metal ions from catalysing the decomposition of peroxygen chemicals, especially hydrogen peroxide.

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Pentetic acid

DTPA 構造式

CAS 番号 : 67-43-6

容量 価格(税別) 在庫状況 数量
100 mg $50 在庫あり
500 mg $110 在庫あり
1 g   お問い合わせ  
5 g   お問い合わせ  

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Based on 3 publication(s) in Google Scholar

Other Forms of Pentetic acid:

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製品説明

Pentetic acid (Diethylenetriaminepentaacetic acid) is an orally active compound with biodegradability used to construct magnetic adsorbent, which can simultaneously remove heavy metal and dye from complex wastewater. Pentetic acid can form strong metal complexes, which prevents metal ions from catalysing the decomposition of peroxygen chemicals, especially hydrogen peroxide[1][2][3][4].

Cellular Effect
Cell Line Type Value Description References
HeLa IC50
264.5 μM
Compound: DTPA
Cytotoxicity against human HeLa cells after 72 hrs by MTS assay
Cytotoxicity against human HeLa cells after 72 hrs by MTS assay
[PMID: 18345610]
HepG2 IC50
38.3 μM
Compound: DTPA
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
[PMID: 29233652]
HT-29 IC50
39.1 μM
Compound: DTPA
Cytotoxicity against human HT29 cells after 72 hrs by MTS assay
Cytotoxicity against human HT29 cells after 72 hrs by MTS assay
[PMID: 18345610]
体外実験

Pentetic acid (0-100 μM, 16 h) inhibits the secretion of elastase in PAO1 cells[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

RT-PCR[5]

Cell Line: PAO1
Concentration: 10, 50, 100 μM
Incubation Time: 16 h
Result: Decreased the expression of lasB gene transcription levels.
臨床実験
分子量

393.35

分子式

C14H23N3O10

CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CN(CCN(CC(O)=O)CC(O)=O)CCN(CC(O)=O)CC(O)=O

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 5 mg/mL (12.71 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5423 mL 12.7113 mL 25.4227 mL
5 mM 0.5085 mL 2.5423 mL 5.0845 mL
10 mM 0.2542 mL 1.2711 mL 2.5423 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始)

C1

×
体積 (開始)

V1

=
濃度 (終了)

C2

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体積 (終了)

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5423 mL 12.7113 mL 25.4227 mL 63.5566 mL
5 mM 0.5085 mL 2.5423 mL 5.0845 mL 12.7113 mL
10 mM 0.2542 mL 1.2711 mL 2.5423 mL 6.3557 mL
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

製品名:
Pentetic acid
製品番号:
HY-B1335
数量:
MCE 日本正規代理店: