Pomolic acid 3-acetate
Pomolic acid 3-acetate is an antitubercular agent with a MIC of 32 μM against Mycobacterium tuberculosis H37Rv.
For research use only. We do not sell to patients.
- CAS No.: 15914-62-2
- Formula: C32H50O5
- Molecular Weight:514.74
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MIC: 32 μM (Mycobacterium tuberculosis H37Rv)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | GI50 |
>100 μM
Compound: 18
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Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay
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[PMID: 32345458] |
| HCT-116 | GI50 |
>100 μM
Compound: 18
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Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTT assay
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[PMID: 32345458] |
| MCF7 | GI50 |
>100 μM
Compound: 18
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Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
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[PMID: 32345458] |
Pomolic acid 3-acetate inhibits JB6 cell transformation with an IC50 of 8.1 μg/mL[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 15914-62-2
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Molecular Weight 514.74
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Formula C32H50O5
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SMILES
OC([C@]12[C@]([C@](O)([C@@H](CC2)C)C)([H])C3=CC[C@@]([C@@]4([C@@](C(C)([C@H](CC4)OC(C)=O)C)([H])CC5)C)([H])[C@]5(C)[C@@]3(CC1)C)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wächter GA, et al. Antitubercular activity of pentacyclic triterpenoids from plants of Argentina and Chile. Phytomedicine. 1999 Nov;6(5):341-5. [Content Brief]
[2]. Carcache-Blanco EJ, et al. Potential cancer chemopreventive agents from Arbutus unedo. Nat Prod Res. 2006 Apr;20(4):327-34. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pomolic acid 3-acetate Related Classifications
HY-N10992 Related Classifications
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