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Cat. No.: HY-159504

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Pregabalinum naproxencarbilum

(Synonyms: Pregabalin naproxencarbil)

Pregabalinum naproxencarbilum (Pregabalin naproxencarbil) is a gabamimetic (GABA) with analgesic effects. Pregabalinum naproxencarbilum is a nonopioid analgesic targeting both inflammatory and neuropathic pain signaling pathways.

For research use only. We do not sell to patients.

CAS No.: 1221072-91-8
Formula: C₂₅H₃₃NO₇
Molecular Weight:459.53

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Pregabalinum naproxencarbilum Chemical Structure

CAS No.: 1221072-91-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vivo

Pregabalinum naproxencarbilum is a single molecule prodrug, it is not active in the gastrointestinal tract but metabolized into Naproxen (HY-15030) and Pregabalin after absorption^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1221072-91-8
Molecular Weight 459.53
Formula C₂₅H₃₃NO₇
SMILES

CC(C)C[C@@H](CC(O)=O)CNC(O[C@H](C)OC([C@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C)=O)=O
Synonyms

Pregabalin naproxencarbil
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pregabalinum naproxencarbilum (Pregabalin naproxencarbil). WHO Drug Information, Vol. 37, No. 4, 2023.

[2]. Jiang GL, et al. Pregabalin naproxencarbil in acute post-bunionectomy pain: a randomized clinical trial. Pain Rep. 2026 Jan 20;11(2):e1424. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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