PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc
PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc can be used as a key intermediate for the synthesis of complete PROTAC molecules.
For research use only. We do not sell to patients.
- Formula: C36H48N6O6S
- Molecular Weight:692.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Description
IC50 & Target
von Hippel-Lindau (VHL)[1]
Chemical Information
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Molecular Weight 692.87
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Formula C36H48N6O6S
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SMILES
O=C([C@H]1N(C[C@@H](C1)O)C(C(C(C)C)C2=CC(N3CC4(CCN(CC4)C(OC(C)(C)C)=O)C3)=NO2)=O)NCC(C=C5)=CC=C5C(SC=N6)=C6C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)