Alkaloids from Cynanchum komarovii with inhibitory activity against the tobacco mosaic virus

  • Phytochemistry. 2001 Dec;58(8):1267-9. doi: 10.1016/s0031-9422(01)00382-x.
T An  1 ,  R Q Huang ,  Z Yang ,  D K Zhang ,  G R Li ,  Y C Yao ,  J Gao
Affiliations
  • 1. Research Institute of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071People's Republic of China.
PMID: 11738420 DOI: 10.1016/s0031-9422(01)00382-x
Abstract

A pyrroloisoquinoline alkaloid, 2,3-dimethoxy-6-(3-oxo-butyl)-7,9,10,11,11a,12-hexahydrobenzo[f]pyrrolo[1,2-b]isoquinoline (1), whose structure was determined by spectroscopic methods, was isolated from the aerial parts of Cynanchum komarovii, together with two known Alkaloids, 7-demethoxytylophorine (2) and 7-demethoxytylophorine N-oxide (3). Alkaloids 2 and 3 had Antiviral activities against tobacco mosaic virus.

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