Structural analysis of lipopolysaccharides from Gram-negative bacteria

  • Biochemistry (Mosc). 2010 Apr;75(4):383-404. doi: 10.1134/s0006297910040012.
D S Kabanov  1 ,  I R Prokhorenko
Affiliations
  • 1. Institute of Basic Biological Problems, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia. [email protected]
PMID: 20618127 DOI: 10.1134/s0006297910040012
Abstract

This review covers data on composition and structure of lipid A, core, and O-polysaccharide of the known lipopolysaccharides from Gram-negative bacteria. The relationship between the structure and biological activity of lipid A is discussed. The data on roles of core and O-polysaccharide in biological activities of lipopolysaccharides are presented. The structural homology of some oligosaccharide sequences of lipopolysaccharides to gangliosides of human cell membranes is considered.

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