New α-Tetralone Galloylglucosides from the Fresh Pericarps of Juglans sigillata

  • Helv Chim Acta. 2010 Feb 1;93(2):10.1002/hlca.200900177. doi: 10.1002/hlca.200900177.
Qing Liu  1 ,  Ping Zhao ,  Xing-Cong Li ,  Melissa R Jacob ,  Chong-Ren Yang ,  Ying-Jun Zhang
Affiliations
  • 1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, P. R. China; (phone: 86-871-5223235; fax: 86-871-5150124;).
PMID: 24223428 DOI: 10.1002/hlca.200900177
Abstract

Three new α-tetralone galloylglucosides (1-3), were isolated from the fresh pericarps of Juglans sigillata (Juglandaceae), together with the six known ones. The structures of the new compounds were determined as 4,6-dihydroxy-α-tetralone-4-O-[6'-O-(3″, 4″,5″-trihydroxybenzoyl)]-β-D-glucopyranoside (1), (4S)-4,5-dihydroxy-α-tetralone-4-O-[6'-O-(3″,4″,5″-trihydroxybenzoyl)]-β-D-glucopyranoside (2) and (4S)-4,5,6-tri-hydroxy-α-tetralone-4-O-[6'-O-(3″,4″,5″-trihydroxybenzoyl)]-β-D-glucopyranoside (3), respectively, on the basis of detailed spectroscopic analyses, and acidic and enzymatic hydrolysis. The antimicrobial activities of the isolated compounds (2, 4 and 7-9) were evaluated.

Keywords
Juglandaceae; Juglans sigillata; antimicrobial activity; α-tetralone galloylglucosides.
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