Recombinant human interleukin 5 is a selective activator of human eosinophil function

  • J Exp Med. 1988 Jan 1;167(1):219-24. doi: 10.1084/jem.167.1.219.
A F Lopez  1 ,  C J Sanderson ,  J R Gamble ,  H D Campbell ,  I G Young ,  M A Vadas
Affiliations
  • 1. Division of Human Immunology, Institute of Medical and Veterinary Science, Adelaide, South Australia.
PMID: 2826636 DOI: 10.1084/jem.167.1.219
Abstract

Human rIL-5 was found to selectively stimulate morphological changes and the function of human eosinophils. This molecule is thus a prime candidate for the selective eosinophilia and eosinophil activation seen in disease.

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