Lupane-Type Triterpenes of Phoradendron vernicosum

  • J Nat Prod. 2017 Nov 22;80(11):3038-3042. doi: 10.1021/acs.jnatprod.7b00177.
Lía S Valencia-Chan  1 ,  Isabel García-Cámara  1 ,  Luis W Torres-Tapia  1 ,  Rosa E Moo-Puc  2 ,  Sergio R Peraza-Sánchez  1
Affiliations
  • 1. Unidad de Biotecnología, Centro de Investigación Científica de Yucatán (CICY) , Calle 43 No. 130, Col. Chuburná de Hidalgo, Mérida, Yucatán, México 97205.
  • 2. Unidad de Investigación Médica Yucatán, Unidad Médica de Alta Especialidad, Centro Médico Ignacio García Téllez, Instituto Mexicano del Seguro Social (IMSS) , Calle 41 No. 439, Col. Industrial, Mérida, Yucatán, México 97200.
PMID: 29120172 DOI: 10.1021/acs.jnatprod.7b00177
Abstract

Three new lupane-type Triterpenes, 3α,24-dihydroxylup-20(29)-en-28-oic acid (1), 3α,23-dihydroxy-30-oxolup-20(29)-en-28-oic acid (2), and 3α,23-O-isopropylidenyl-3α,23-dihydroxylup-20(29)-en-28-oic acid (3), together with eight known compounds (4-11) were isolated from a methanol extract of Phoradendron vernicosum aerial parts. The chemical structures of 1-3 were determined on the basis of spectroscopic data interpretation. The isolated compounds were tested against seven human Cancer cell lines and two normal cell lines.