CircPDXDC1 Induces Mitochondrial Dysfunction and Autophagy Dysfunction in Acute Myocardial Infarction by Promoting ELAVL1 Ubiquitination

  • Appl Biochem Biotechnol. 2026 Jan 4. doi: 10.1007/s12010-025-05503-x.
Lei Geng  #  1 ,  WenWen Tu  #  2 ,  Jing Gao  1 ,  JianYin Huang  3
Affiliations
  • 1. Department of Emergency Medicine, Shanghai Sixth People's Hospital, No. 600, Yishan Road, Shanghai City, Xuhui District, 200233, China.
  • 2. Huadong Pharmaceutical Co., Ltd, Shanghai City, 200040, China.
  • 3. Department of Emergency Medicine, Shanghai Sixth People's Hospital, No. 600, Yishan Road, Shanghai City, Xuhui District, 200233, China. [email protected].
  • # Contributed equally.
PMID: 41484747 DOI: 10.1007/s12010-025-05503-x
Keywords
Acute myocardial infarction; Autophagy dysfunction; CircPDXDC1; ELAVL1; Mitochondrial dysfunction; Ubiquitination.
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