Hesperetin alleviates neuronal pyroptosis by promoting mitophagy via DHCR24/BACE1 signaling pathway after subarachnoid hemorrhage in mice

  • Apoptosis. 2026 Jan 10;31(1):21. doi: 10.1007/s10495-025-02238-2.
Hongjiang Ye  1 ,  Xin Wang  2 ,  Yidan Liang  1 ,  Yin Tang  3 ,  Jiahe Tan  1 ,  Yinrui Ma  1 ,  Daiqi Xu  1 ,  Han Xiong  1 ,  Yiming Zhuang  1 ,  Wenqiao Fu  4 ,  Zhaohui He  5
Affiliations
  • 1. Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
  • 2. Department of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
  • 3. Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
  • 4. Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. [email protected].
  • 5. Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. [email protected].
PMID: 41518524 DOI: 10.1007/s10495-025-02238-2
Keywords
BACE1; DHCR24; Hesperetin; Mitophagy; Pyroptosis; Subarachnoid hemorrhage.
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