2. (R)-2-Amino-5,5,5-trifluoropentanoic acid

(R)-2-Amino-5,5,5-trifluoropentanoic acid is a leucine antagonist. (R)-2-Amino-5,5,5-trifluoropentanoic acid increases Sestrin2 binding to GATOR2. (R)-2-Amino-5,5,5-trifluoropentanoic acid can be used in research on diabetes, neurodegenerative diseases, immune diseases, and cancer.

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(R)-2-Amino-5,5,5-trifluoropentanoic acid

(R)-2-Amino-5,5,5-trifluoropentanoic acid Chemical Structure

CAS No. : 122565-29-1

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(R)-2-Amino-5,5,5-trifluoropentanoic acid Related Antibodies

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Description

(R)-2-Amino-5,5,5-trifluoropentanoic acid is a leucine antagonist. (R)-2-Amino-5,5,5-trifluoropentanoic acid increases Sestrin2 binding to GATOR2. (R)-2-Amino-5,5,5-trifluoropentanoic acid can be used in research on diabetes, neurodegenerative diseases, immune diseases, and cancer[1].

In Vitro

(R)-2-Amino-5,5,5-trifluoropentanoic acid (Compound I-7) (25 μM) increases Sestrin2-GATOR2 binding by at least 40% relative to leucine when tested in a cell-free Sestrin2-GATOR2 interaction assay[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(R)-2-Amino-5,5,5-trifluoropentanoic acid Related Antibodies
Molecular Weight

171.12

Formula

C5H8F3NO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C([C@H](C(O)=O)N)CC(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥95.0%

SDS (394 KB)

COA (244 KB)

Handling Instructions (2659 KB)
References
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(R)-2-Amino-5,5,5-trifluoropentanoic acid Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R)-2-Amino-5,5,5-trifluoropentanoic acid122565-29-1Sestrin2-GATOR2Sestrin2GATOR2leucineleucine antagonistInhibitorinhibitorinhibit

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