(R)-2-Amino-5,5,5-trifluoropentanoic acid
Based on 1 Customer Validation
(R)-2-Amino-5,5,5-trifluoropentanoic acid is a leucine antagonist. (R)-2-Amino-5,5,5-trifluoropentanoic acid increases Sestrin2 binding to GATOR2. (R)-2-Amino-5,5,5-trifluoropentanoic acid can be used in research on diabetes, neurodegenerative diseases, immune diseases, and cancer.
For research use only. We do not sell to patients.
- CAS No.: 122565-29-1
- Formula: C5H8F3NO2
- Molecular Weight:171.12
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
In Vitro
(R)-2-Amino-5,5,5-trifluoropentanoic acid (Compound I-7) (25 μM) increases Sestrin2-GATOR2 binding by at least 40% relative to leucine when tested in a cell-free Sestrin2-GATOR2 interaction assay[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 122565-29-1
-
Appearance Solid
-
Molecular Weight 171.12
-
Formula C5H8F3NO2
-
Color White to off-white
-
SMILES
C([C@H](C(O)=O)N)CC(F)(F)F
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
-
Data Sheet (265 KB)
-
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)