ADCK3 Protein, Human (sf9, His, GST)
ADCK3 Protein, Human (sf9, His, GST) is the recombinant human-derived ADCK3, expressed by sf9 insect cells, with His, GST labeled tag.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
ADCK3 Protein, Human (sf9, His, GST) is the recombinant human-derived ADCK3, expressed by sf9 insect cells, with His, GST labeled tag.
Background
ADCK3 is an atypical kinase involved in the biosynthesis of coenzyme Q (also known as ubiquinone), an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity remains unclear: it may act as a protein kinase mediating the phosphorylation of COQ3 (by similar). Other reports suggest it functions as a small molecule kinase, possibly a lipid kinase phosphorylating a prenyl lipid in the ubiquinone biosynthesis pathway, supported by its ability to bind coenzyme Q lipid intermediates. However, this small molecule kinase activity was not confirmed by another study (by similar). It exhibits unusual selectivity for ADP binding over ATP.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag His;GST
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Accession
Q8NI60-1 (S135-Q647)
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Gene ID56997
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Protein Length
Partial
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Synonyms
COQ8A; Chaperone-ABC1 (Activity Of Bc1 Complex, S.Pombe)-Like; Prev. ADCK3; Chaperone, ABC1 Activity Of Bc1 Complex Homolog; Prev. CABC1; Chaperone Activity Of Bc1 Complex-Like; SCAR9; Atypical Kinase ADCK3, Mitochondrial; COQ8; AarF Domain Containing Kin
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AA Sequence
SSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEKARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSEDPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRDLLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAKSIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ
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Predicted Molecular Mass
85.9 kDa
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Purity
≥ 80%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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