AMIGO2 Protein, Mouse (HEK293, His)
AMIGO2 Protein, crucial for the survival of cultured cerebellar granule neurons, mediates homophilic and heterophilic cell interactions with AMIGO1 or AMIGO3. Its intracellular domain may contribute to signal transduction, and AMIGO2 exhibits self-binding ability along with binding to AMIGO1 and AMIGO3 proteins. AMIGO2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived AMIGO2 protein, expressed by HEK293 , with C-His labeled tag.
- Species: Mouse
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
AMIGO2 Protein, crucial for the survival of cultured cerebellar granule neurons, mediates homophilic and heterophilic cell interactions with AMIGO1 or AMIGO3. Its intracellular domain may contribute to signal transduction, and AMIGO2 exhibits self-binding ability along with binding to AMIGO1 and AMIGO3 proteins. AMIGO2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived AMIGO2 protein, expressed by HEK293 , with C-His labeled tag.
AMIGO2 Protein is essential for the depolarization-dependent survival of cultured cerebellar granule neurons. It plays a crucial role in mediating both homophilic and heterophilic cell-cell interactions with AMIGO1 or AMIGO3. Additionally, it is speculated to contribute to signal transduction through its intracellular domain. Furthermore, AMIGO2 has the capability to bind to itself, as well as to AMIGO1 and AMIGO3 proteins.
Technical Parameters
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Species Mouse
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Source HEK293
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Tag C-8*His
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Accession
Q80ZD9 (M39-T397)
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Molecular Construction
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N-term
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AMIGO2 (M39-T397)
Accession # Q80ZD9 -
8*His
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C-term
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Protein Length
Extracellular Domain
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Synonyms
AMIGO2; Differentially Expressed In Gastric Adenocarcinoma; Adhesion Molecule With Ig Like Domain 2; Amphoterin-Induced Gene And Open Reading Frame 2; ALI1; Transmembrane Protein AMIGO2; DEGA; Amphoterin Induced Gene 2; Differentially Expressed In Gastric
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AA Sequence
MCPTACICATDIVSCTNKNLSKVPGNLFRLIKRLDLSYNRIGLLDADWIPVSFVKLSTLILRHNNITSISTGSFSTTPNLKCLDLSSNRLKSVKSATFQELKALEVLLLYNNHISYLDPAAFGGLSHLQKLYLSGNFLTQFPMDLYTGRFKLADLTFLDVSYNRIPSIPMHHINLVPGRQLRGIYLHGNPFVCDCSLYSLLIFWYRRHFSSVMDFKNDYTCRLWSDSRHSHQLQLLQESFLNCSYSVINGSFHALGFIHEAQVGERAIVHCDSKTGNGNTDFIWVGPDNRLLEPDKDMGNFRVFYNGSLVIENPGFEDAGVYSCIAMNRQRLLNETVDIMINVSNFTINRSHAHEAFNT
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Predicted Molecular Mass
41.8 kDa
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Molecular Weight
Approximately 55-65 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Glycosylation
Yes
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Purity
≥ 95%, as determined by Bis-Tris PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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