2. Recombinant Proteins
  3. Biotinylated Proteins
  4. C-Reactive Protein, Human (Biotinylated, HEK293)

C-Reactive Protein, Human (Biotinylated, HEK293)

Cat. No.: HY-P77514
Handling Instructions

C-Reactive Protein, an acute-phase protein, is a marker of inflammation and is produced by the liver. It is used as a diagnostic tool to assess the presence and severity of inflammation in various diseases. C-Reactive Protein's role in inflammation detection and its clinical significance in disease management make it a subject of interest in medical research. C-Reactive Protein, Human (Biotinylated, HEK293) is the recombinant human-derived C-Reactive protein, expressed by HEK293 , with tag free. The total length of C-Reactive Protein, Human (Biotinylated, HEK293) is 224 a.a., with molecular weight of ~23 KDa.

For research use only. We do not sell to patients.

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Description

C-Reactive Protein, an acute-phase protein, is a marker of inflammation and is produced by the liver. It is used as a diagnostic tool to assess the presence and severity of inflammation in various diseases. C-Reactive Protein's role in inflammation detection and its clinical significance in disease management make it a subject of interest in medical research. C-Reactive Protein, Human (Biotinylated, HEK293) is the recombinant human-derived C-Reactive protein, expressed by HEK293 , with tag free. The total length of C-Reactive Protein, Human (Biotinylated, HEK293) is 224 a.a., with molecular weight of ~23 KDa.
Background

C-Reactive Protein (CRP) exhibits various functions related to host defense. It facilitates agglutination, bacterial capsular swelling, phagocytosis, and complement fixation by binding to phosphorylcholine in a calcium-dependent manner. CRP is also capable of interacting with DNA and histones, and it may scavenge nuclear material that is released from damaged circulating cells.
Species

Human
Source

HEK293
Tag

Tag Free
Accession

P02741 (M1-P224)
Gene ID
Molecular Construction
N-term
C-Reactive (M1-P224)
Accession # P02741
C-term
Synonyms
C-Reactive Protein; CRP; PTX1
Molecular Weight

Approximately 23 kDa.
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

C-Reactive Protein, Human (Biotinylated, HEK293) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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