1. Recombinant Proteins
  2. Enzymes & Regulators Kinases
  3. Transferases (EC 2) Serine/Threonine Kinase Proteins CAMK
  4. CAMK1
  5. CaMK1a/CAMK1
  6. CAMKI alpha/CAMK1 Protein, Human (Active)

CAMKI alpha/CAMK1 Protein, Human, a recombinant human CAMK1 produced in HEK293 cells. CAMK1 is involved in multiple cell functions, including calmodulin binding, ATP binding, signal transduction, development and cell differentiation.

For research use only. We do not sell to patients.

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Description

CAMKI alpha/CAMK1 Protein, Human, a recombinant human CAMK1 produced in HEK293 cells. CAMK1 is involved in multiple cell functions, including calmodulin binding, ATP binding, signal transduction, development and cell differentiation[1].

Background

Calcium/calmodulin-dependent protein kinase (CAMKs) can control a wide range of cancer-related functions in multiple tumour types. The PPI network suggested that CALM1, CALM3, CREB1, CALM2, SYN1, NOS3, ATF1, GAPDH, PPM1F and FBXL12 were important significant genes associated with CAMK1[1].

Species

Human

Source

E. coli

Tag

Tag Free

Accession

NP_003647.1 (L2-L370, with additional two amino acids Gly & Pro at the N-terminus)

Gene ID

8536

Molecular Construction
N-term
Gly-Pro
CAMK1 (L2-L370)
Accession # NP_003647.1
C-term
Protein Length

Full Length of Mature Protein

Synonyms
rHuCAMK1, His; Calcium/Calmodulin-Dependent Protein Kinase Type 1; CaM Kinase I; CaMKI-Alpha; CAMK1
AA Sequence

MLGAVEGPRWKQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKLQLGTSQEGQGQTASHGELLTPVAGGPAAGCCCRDCCVEPGTELSPTLPHQLHHHHHH

Predicted Molecular Mass
41.5 kDa
Molecular Weight

Approximately 42 kDa

Purity

≥ 90%, as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
CAMKI alpha/CAMK1 Protein, Human (Active)
Cat. No.:
HY-P705662
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