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  3. T Cell CD Proteins
  4. CD1b
  5. CD1B Protein, Human (HEK293, Fc)

CD1B Protein, Human (HEK293, Fc)

Cat. No.: HY-P75438
Handling Instructions

The CD1B protein is a key antigen-presenting molecule that binds self- and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T cells. As a B2M (beta-2-microglobulin) heterodimer, CD1B is crucially involved in immune surveillance and responses. CD1B Protein, Human (HEK293, Fc) is the recombinant human-derived CD1B protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD1B Protein, Human (HEK293, Fc) is 286 a.a., with molecular weight of 59-69 kDa.

For research use only. We do not sell to patients.

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Description

The CD1B protein is a key antigen-presenting molecule that binds self- and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T cells. As a B2M (beta-2-microglobulin) heterodimer, CD1B is crucially involved in immune surveillance and responses. CD1B Protein, Human (HEK293, Fc) is the recombinant human-derived CD1B protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD1B Protein, Human (HEK293, Fc) is 286 a.a., with molecular weight of 59-69 kDa.

Background

The CD1B protein serves as a key antigen-presenting molecule, demonstrating the ability to bind both self and non-self lipid and glycolipid antigens, thereby facilitating their presentation to T-cell receptors on natural killer T-cells. Forming a heterodimeric complex with B2M (beta-2-microglobulin), this protein plays a crucial role in immune surveillance and response. Its interaction with saposin C further enhances its functional repertoire, contributing to the intricate processes underlying T-cell recognition and activation in response to a diverse array of antigens.

Species

Human

Source

HEK293

Tag

C-hFc

Accession

P29016 (S18-S303)

Gene ID

910  [NCBI]

Molecular Construction
N-term
CD1B (S18-S303)
Accession # P29016
hFc
C-term
Synonyms
T-cell surface glycoprotein CD1b; CD1b; CD1B
Molecular Weight

59-69 kDa

Purity

Greater than 88% as determined by reducing SDS-PAGE

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

CD1B Protein, Human (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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CD1B Protein, Human (HEK293, Fc)
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HY-P75438
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