2. Recombinant Proteins
  3. Cytokines and Growth Factors Immune Checkpoint Proteins CD Antigens
  4. TNF Superfamily Stimulatory Immune Checkpoint Molecules T Cell CD Proteins B Cell CD Proteins NK Cell CD Proteins Macrophage CD Proteins Stem Cell CD Proteins
  5. TNF Receptor Superfamily CD27
  6. CD27/TNFRSF7 Protein, Mouse (HEK293, His)

CD27/TNFRSF7 Protein, Mouse (HEK293, His)

Cat. No.: HY-P76216
Handling Instructions

CD27/NFRSF7 Protein acts as a receptor for CD70/CD27L, supporting activated T-cell survival and potentially influencing apoptosis through interactions with SIVA1. It forms homodimers and engages with SIVA1 and TRAF2, indicating diverse roles in cellular processes. CD27/TNFRSF7 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD27/TNFRSF7 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD27/TNFRSF7 Protein, Mouse (HEK293, His) is 159 a.a., with molecular weight of ~35 KDa.

For research use only. We do not sell to patients.

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Description

CD27/NFRSF7 Protein acts as a receptor for CD70/CD27L, supporting activated T-cell survival and potentially influencing apoptosis through interactions with SIVA1. It forms homodimers and engages with SIVA1 and TRAF2, indicating diverse roles in cellular processes. CD27/TNFRSF7 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD27/TNFRSF7 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD27/TNFRSF7 Protein, Mouse (HEK293, His) is 159 a.a., with molecular weight of ~35 KDa.
Background

The CD27/NFRSF7 Protein serves as a receptor for CD70/CD27L and is implicated in the survival of activated T-cells. Additionally, it may play a role in apoptosis by interacting with SIVA1. The protein forms homodimers and engages with SIVA1 and TRAF2, suggesting its involvement in diverse cellular processes.
Species

Mouse
Source

HEK293
Tag

C-His
Accession

P41272 (P24-R182)
Gene ID

21940  [NCBI]
Molecular Construction
N-term
CD27 (P24-R182)
Accession # P41272
His
C-term
Synonyms
CD27 antigen; T cell activation antigen CD27; T14; TNFRSF7
Molecular Weight

Approximately 35 kDa.
Purity

Greater than 95% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

CD27/TNFRSF7 Protein, Mouse (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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