CD6 Protein, Cynomolgus (HEK293, His)
CD6 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD6 protein, expressed by HEK293, with C-His tag.
- Species: Cynomolgus
- Source: HEK293
-
Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Technical Parameters
-
Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
CD6 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD6 protein, expressed by HEK293, with C-His tag.
Background
The CD6 protein is situated on the outer membrane of T-lymphocytes and various other immune cells. Featuring three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule, this protein plays a crucial role in sustaining T cell activation. Additionally, there is evidence suggesting an association between this gene and susceptibility to multiple sclerosis. Multiple transcript variants, encoding diverse isoforms, have been identified for this gene, with biased expression observed in lymph node, appendix, and nine other tissues.
Technical Parameters
-
Species Cynomolgus
-
Source HEK293
-
Tag C-8*His
-
Accession
XP_005577746 (H18-E398)
-
Gene ID102143944
-
Protein Length
Partial
-
Synonyms
CD6; Tp120; CD6 Molecule; T12; T-Cell Differentiation Antigen CD6; Alternative Protein CD6; CD6 Antigen; TP120
-
AA Sequence
HLSPAPSDQLNASSAESEVWQPGERLPVRLTNGSSSCSGTVEVRLRASWEPVCWALWDSRAAEAVCRALDCGGAEAATLLPRPTPELPPPPAAGNTSAAANATLAGAPALLCSGTEWQLCEVVEHACRSDGRRARVICAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQAVPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPGQHYCGHKEDAGVVCSEHQSWRLTGGADACEGQVEVHFRGVWNTVCDSEWYTSEAKVLCQSLGCGTVIERPKGLPHSLSGRMYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTSEVPASVQTVTTESSVTVKLENKESRE
-
Predicted Molecular Mass
41.8 kDa
-
Molecular Weight
Approximately 70-85 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
-
Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz
