CDCP1 Protein, Mouse (HEK293, Fc)

The CDCP1 protein has been implicated in cell adhesion and matrix association, suggesting a role in important cellular interactions. Its phosphorylation suggests a dynamic function in regulating anchorage, migration, proliferation, or differentiation. CDCP1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CDCP1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CDCP1 Protein, Mouse (HEK293, Fc) is 666 a.a., with molecular weight of ~117 kDa.

CDCP1 Protein appears to be involved in cell adhesion and cell matrix association, suggesting a role in mediating interactions crucial for cellular processes. Its potential involvement in the regulation of anchorage versus migration or proliferation versus differentiation, as indicated by its phosphorylation, implies a dynamic role in modulating cell behavior. Additionally, CDCP1 may serve as a novel marker for leukemia diagnosis and immature hematopoietic stem cell subsets, providing potential diagnostic and therapeutic insights. As a member of the tetraspanin web implicated in tumor progression and metastasis, CDCP1 interacts with key molecules including CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4, the serine protease ST14/MT-SP1, SRC, and PRKCG/protein kinase C gamma. The diversity of its interactions underscores its potential impact on cellular processes and suggests a multifaceted role in both normal and pathological conditions. Further exploration of CDCP1's functions and regulatory mechanisms could provide deeper insights into its contributions to cellular dynamics and its potential as a therapeutic target.

Mouse

HEK293

C-hFc

Q5U462 (M1-L666)

109332  [NCBI]

Approximately 117 kDa

Greater than 80% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.