CDCP1 Protein, Mouse (HEK293, Fc)
The CDCP1 protein has been implicated in cell adhesion and matrix association, suggesting a role in important cellular interactions. Its phosphorylation suggests a dynamic function in regulating anchorage, migration, proliferation, or differentiation. CDCP1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CDCP1 protein, expressed by HEK293 , with C-hFc labeled tag.
- Species: Mouse
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Biological Activity
Description
The CDCP1 protein has been implicated in cell adhesion and matrix association, suggesting a role in important cellular interactions. Its phosphorylation suggests a dynamic function in regulating anchorage, migration, proliferation, or differentiation. CDCP1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CDCP1 protein, expressed by HEK293 , with C-hFc labeled tag.
Background
CDCP1 Protein appears to be involved in cell adhesion and cell matrix association, suggesting a role in mediating interactions crucial for cellular processes. Its potential involvement in the regulation of anchorage versus migration or proliferation versus differentiation, as indicated by its phosphorylation, implies a dynamic role in modulating cell behavior. Additionally, CDCP1 may serve as a novel marker for leukemia diagnosis and immature hematopoietic stem cell subsets, providing potential diagnostic and therapeutic insights. As a member of the tetraspanin web implicated in tumor progression and metastasis, CDCP1 interacts with key molecules including CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4, the serine protease ST14/MT-SP1, SRC, and PRKCG/protein kinase C gamma. The diversity of its interactions underscores its potential impact on cellular processes and suggests a multifaceted role in both normal and pathological conditions. Further exploration of CDCP1's functions and regulatory mechanisms could provide deeper insights into its contributions to cellular dynamics and its potential as a therapeutic target.
Technical Parameters
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Species Mouse
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Source HEK293
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Tag C-hFc
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Accession
Q5U462 (S30-L666)
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Molecular Construction
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N-term
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CDCP1 (S30-L666)
Accession # Q5U462 -
hFc
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C-term
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Protein Length
Extracellular Domain
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Synonyms
CDCP1; Subtractive Immunization M Plus HEp3-Associated 135 KDa Protein; CUB Domain Containing Protein 1; Transmembrane And Associated With Src Kinases; SIMA135; Membrane Glycoprotein Gp140; CUB Domain-Containing Protein 1; TRASK; CD318; CD318 Antigen
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AA Sequence
SEIALPQRSGVTVSIKLGNPALPVKICYIVMSRQHITELIIRPGERKSFTFSCSNPEKHFVLKIEKNIDCMSGPCPFGEVHLQPSTSELPILNRTFIWDVRAHKSIGLELQFATPRLRQIGPGESCADGVTHSISGHIDATEVRIGTFCSNGTVSRIKMQEGVKMALHLPWFHRRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANYPGGFPEDELMTWQFVVPAHLRASVSFLNFNVSNCERKEERVEYYIPGSTTNPEVFRLEDKQPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQRPQDESNKTYMVDLSRERTMSLTIEPRPVKHGRRFVPGCFVCLESRTCSTNVTLTAGSIHKISFLCDDLTRLWVNVEKTLSCLDHRYCYRQSFKLQVPDYILQLPVQLHDFSWKLLVPKDKLSLMLVPGQKLQQHTQERPCNTSFGYHVTSTTPGQDLYFGSFCSGGSIEKIQVKQNSSVTLRAYAPSFQQEVSKQGLIVSYTPYFKEEGIFTVTPDTKNKVYLRSPNWDRGLPALSSVSWNISVPSNQVACLTVLKERSGLACQSGRAFMIIQEQQSRAEEIFSLEEEVLPKPSFHHHSFWVNISNCSPMNGKQLDLLFWVTLTPRTVDL
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Predicted Molecular Mass
98.8 kDa
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Molecular Weight
Approximately 117 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Glycosylation
Yes
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Purity
≥ 80%, as determined by reducing SDS-PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)