CDCP1 Protein, Rat (HEK293, His)

CDCP1 is a cell surface glycoprotein that may contribute to autoimmune diseases such as encephalomyelitis, multiple sclerosis, and inflammatory arthritis. CDCP1 mediates anti-adhesion and anti-migration by negatively regulating integrin receptors. CDCP1 promotes tumor proliferation and metastasis by activating MAPK/ERK and AKT signaling pathways. CDCP1 Protein, Rat (HEK293, His) is the recombinant rat-derived CDCP1 protein, expressed by HEK293 , with C-His labeled tag.

CDCP1, a cell surface glycoprotein, is a ligand for CD6, a receptor molecule expressed on certain T cells that may play a role in T cell migration and chemotaxis. CDCP1 may lead to autoimmune diseases such as encephalomyelitis, multiple sclerosis and inflammatory arthritis. CDCP1 mediates anti-adhesion and anti-migration by negatively regulating integrin receptors. CDCP1 promotes tumor proliferation and metastasis by activating MAPK/ERK and AKT signaling pathways^[1][2][3].

Rat

HEK293

C-8*His

D3ZVA1 (S29-T666)

301082  [NCBI]

Partial

SEIALPRGSDITVHIKLVSPALPVKFCYIVVSRQHVTELTIRPGERKSFTFSCNNPEKHYVLKIEKNIDCMSGPCPFGEVRLQPSKSELPILNRTYIWDVRAHKSIGLELQFATPRLRQIGPGESCADGVTHSISGHIDATEVRIGTFCSNGTVSRIKMQEGVKMALHLPWFHPRNISGFSIANRSSIKRLCIIESVFEGEGSATLMSANYPGGFPEDELMTWQFVVPAHLRASVSFLNFNVSNCERKEERVEYYIPGSTTNPEVFRLEDQQPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQRPQNESNITYMVDLSQERTMSLTIEPRPVKHGRRFVPGCFVCLDSRTCSTNVTLTAGSKHKISFLCDDLARLWMNVEKTLSCLDHRYYYGKSFNLQVPKDILQLPVQLHDFSWKLLVPKDRLGLMLVPGQKLQQHTRERPCNTSFGYQVASTTPGQDLYFGSFCPGGSIEKIQVKQNSSVTLRTYAPGFQQEVSKQVLTVSLIPYFKEEGIFTVTPDSKNKVYLRSPNWDRGLPALSSVSWNISVPSNQVACLTFFRERSGLACQSGRAFMIIQEQQTRAEEIFSLEEEVLPKPSFHHHSFWVNISNCSPMNGKQLDLLFWVTLTPRTVDLT

90-120 kDa

≥ 95%, as determined by Bis-Tris PAGE.

Lyophilized powder.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4, 8% trehalose.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.