Claudin-9/CLDN9 Protein-VLP, Human (HEK293)

Claudin-9/CLDN9 Protein-VLP, Human (HEK293) is recommended for animal immunization, ELISA. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays. If VLP control is required, it is recommended HY-P705433.

Claudin-9/CLDN9 Protein-VLP assumes a pivotal role in the specific obliteration of the intercellular space within tight junctions, employing calcium-independent cell-adhesion activity. Notably, in the context of microbial infection, this protein acts as a receptor facilitating the entry of hepatitis C virus (HCV) into hepatic cells. The dual functionality of Claudin-9/CLDN9 underscores its significance in regulating cell adhesion at tight junctions, contributing to the maintenance of tissue integrity, while also serving as a crucial entry point for HCV, highlighting its relevance in viral infection processes.

Human

HEK293

Tag Free

O95484 (M1-V217)

9080

Full Length

MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLTAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGLLCCTCPPPQVERPRGPRLGYSIPSRSGASGLDKRDYV

Purity analysis by SDS-PAGE is not available for VLP proteins.

<1 EU/μg, determined by LAL method.