Claudin-9/CLDN9 Protein-VLP, Human (HEK293)
Claudin-9/CLDN9 Protein-VLP, Human (HEK293) is recommended for animal immunization, ELISA. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays. If VLP control is required, it is recommended HY-P705433.
- Species: Human
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
Claudin-9/CLDN9 Protein-VLP, Human (HEK293) is recommended for animal immunization, ELISA. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays. If VLP control is required, it is recommended HY-P705433.
Background
Claudin-9/CLDN9 Protein-VLP assumes a pivotal role in the specific obliteration of the intercellular space within tight junctions, employing calcium-independent cell-adhesion activity. Notably, in the context of microbial infection, this protein acts as a receptor facilitating the entry of hepatitis C virus (HCV) into hepatic cells. The dual functionality of Claudin-9/CLDN9 underscores its significance in regulating cell adhesion at tight junctions, contributing to the maintenance of tissue integrity, while also serving as a crucial entry point for HCV, highlighting its relevance in viral infection processes.
Technical Parameters
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Species Human
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Source HEK293
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Tag Tag Free
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Accession
O95484 (M1-V217)
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Gene ID9080
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Protein Length
Full Length
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Synonyms
CLDN9; Claudin-9; Claudin 9; DFNB116
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AA Sequence
MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLTAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGLLCCTCPPPQVERPRGPRLGYSIPSRSGASGLDKRDYV
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Predicted Molecular Mass
22.9 kDa
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Purity
Purity analysis by SDS-PAGE is not available for VLP proteins.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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