CLEC10A/CD301 Protein, Mouse (HEK293, Fc)
Based on 1 Customer Validation
CLEC10A/CD301 has predicted carbohydrate-binding activity and plays an upstream role in connective tissue replacement in inflammatory responses and wound healing. This protein is expected to be located on the membrane and be an integral part of the membrane structure, being active on the outside of the plasma membrane. CLEC10A/CD301 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CLEC10A/CD301 protein, expressed by HEK293 , with N-hFc labeled tag.
- Species: Mouse
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
CLEC10A/CD301 has predicted carbohydrate-binding activity and plays an upstream role in connective tissue replacement in inflammatory responses and wound healing. This protein is expected to be located on the membrane and be an integral part of the membrane structure, being active on the outside of the plasma membrane. CLEC10A/CD301 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CLEC10A/CD301 protein, expressed by HEK293 , with N-hFc labeled tag.
Background
CLEC10A/CD301, a protein with predicted carbohydrate binding activity, plays a role upstream of connective tissue replacement involved in inflammatory response and wound healing. Anticipated to be located in the membrane and serve as an integral component of membrane structure, this protein is predicted to be active on the external side of the plasma membrane. Expression of CLEC10A is detected in various structures, including cartilage, dermis, embryo mesenchyme, metencephalon part of the 4th ventricle choroid plexus, and spinal cord marginal layer. The biased expression of CLEC10A in tissues such as mammary gland (RPKM 20.4) and bladder (RPKM 15.0) suggests its potential involvement in diverse physiological processes across different tissues.
MCE Validation Data
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Purity - SDS-PAGE
Purity - SDS-PAGE
Technical Parameters
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Species Mouse
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Source HEK293
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Tag N-hFc
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Accession
NP_001191181.1 (Q58-S305)
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Molecular Construction
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N-term
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hFc
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CLEC10A/CD301 (Q58-S305)
Accession # NP_001191181.1 -
C-term
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Protein Length
Partial
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Synonyms
CLEC10A; DC-Asialoglycoprotein Receptor; Prev. CLECSF13; MGL; Prev. CLECSF14; C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin, Superfamily Member 13 (Macrophage-Derived); HML; CDNA FLJ78539, Highly Similar To Homo Sapiens C-Type Lectin
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AA Sequence
QNSQLRRDLGTLRATLDNTTSKIKAEFQSLDSRADSFEKGISSLKVDVEDHRQELQAGRDLSQKVTSLESTVEKREQALKTDLSDLTDHVQQLRKDLKALTCQLANLKNNGSEVACCPLHWTEHEGSCYWFSESEKSWPEADKYCRLENSHLVVVNSLEEQNFLQNRLANVVSWIGLTDQNGPWRWVDGTDFEKGFKNWAPLQPDNWFGHGLGGGEDCAHITTGGPWNDDVCQRTFRWICEMKLAKES
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Molecular Weight
Approximately 58 kDa, based on SDS-PAGE under reducing conditions.
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Glycosylation
Yes
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder
Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (237 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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