Collagen alpha-1(XV) chain/COL15A1 Protein, Human (His)
Collagen XV alpha 1 (COL15A1) is a structural protein crucial for stabilizing microvessels and muscle cells, playing a key role in cardiac and skeletal muscle tissues. Its structural support contributes to microvascular and muscle integrity. Additionally, COL15A1 exhibits a potent anti-angiogenic effect, inhibiting angiogenesis and suggesting its role in regulating blood vessel formation. Collagen XV alpha 1/COL15A1 Protein, Human (His) is the recombinant human-derived Collagen XV alpha 1/COL15A1, expressed by E. coli Cell-free, with N-10*His labeled tag. The total length of Collagen XV alpha 1/COL15A1 Protein, Human (His) is 189 a.a..
- Species: Human
- Source: E. coli
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
Collagen XV alpha 1 (COL15A1) is a structural protein crucial for stabilizing microvessels and muscle cells, playing a key role in cardiac and skeletal muscle tissues. Its structural support contributes to microvascular and muscle integrity. Additionally, COL15A1 exhibits a potent anti-angiogenic effect, inhibiting angiogenesis and suggesting its role in regulating blood vessel formation. Collagen XV alpha 1/COL15A1 Protein, Human (His) is the recombinant human-derived Collagen XV alpha 1/COL15A1, expressed by E. coli Cell-free, with N-10*His labeled tag. The total length of Collagen XV alpha 1/COL15A1 Protein, Human (His) is 189 a.a..
Background
Collagen XV alpha 1 (COL15A1) is a structural protein with a key role in stabilizing microvessels and muscle cells, functioning prominently in both cardiac and skeletal muscle tissues. The protein's structural support contributes to the maintenance and integrity of microvascular and muscle structures. Additionally, COL15A1 exhibits a potent anti-angiogenic effect, as evidenced by its inhibitory action on angiogenesis, suggesting its involvement in the regulation of blood vessel formation.
Technical Parameters
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Species Human
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Source E. coli
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Tag N-10*His
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Accession
P39059 (H40-P228)
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Gene ID1306
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Protein Length
Partial
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Synonyms
COL15A1; Collagen Alpha-1(XV) Chain; Collagen Type XV Alpha 1 Chain; Collagen XV, Alpha-1 Polypeptide; Collagen Type XV Proteoglycan; Endostatin-XV; Collagen, Type XV, Alpha 1; Restin
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AA Sequence
HLDLTQLIGVPLPSSVSFVTGYGGFPAYSFGPGANVGRPARTLIPSTFFRDFAISVVVKPSSTRGGVLFAITDAFQKVIYLGLRLSGVEDGHQRIILYYTEPGSHVSQEAAAFSVPVMTHRWNRFAMIVQGEEVTLLVNCEEHSRIPFQRSSQALAFESSAGIFMGNAGATGLERFTGSLQQLTVHPDP
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Predicted Molecular Mass
26.5 kDa
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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