CSNK1G1 Protein, Human (Active, sf9, GST)
The CSNK1G1 protein is a member of the casein kinase family that preferentially phosphorylates acidic proteins, including casein, exhibiting broad substrate specificity. Functionally, it actively participates in the Wnt signaling pathway and regulates cellular responses. CSNK1G1 Protein, Human (sf9, GST) is the recombinant human-derived CSNK1G1, expressed by Sf9 insect cells, with GST labeled tag. The total length of CSNK1G1 Protein, Human (sf9, GST) is 421 a.a..
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
The CSNK1G1 protein is a member of the casein kinase family that preferentially phosphorylates acidic proteins, including casein, exhibiting broad substrate specificity. Functionally, it actively participates in the Wnt signaling pathway and regulates cellular responses. CSNK1G1 Protein, Human (sf9, GST) is the recombinant human-derived CSNK1G1, expressed by Sf9 insect cells, with GST labeled tag. The total length of CSNK1G1 Protein, Human (sf9, GST) is 421 a.a..
Background
CSNK1G1, a serine/threonine-protein kinase belonging to the casein kinase family, is characterized by its operational definition involving the preferential phosphorylation of acidic proteins, including caseins. With a broad substrate specificity, it has the capability to phosphorylate a diverse array of proteins. Functionally, CSNK1G1 actively participates in the intricate Wnt signaling pathway, contributing to the modulation of cellular responses. Moreover, it plays a regulatory role in the rapid transmission of synaptic signals mediated by glutamate, demonstrating its involvement in synaptic processes and neurotransmitter signaling, as observed in other members of the casein kinase family. Notably, CSNK1G1 phosphorylates CLSPN, suggesting its role in influencing cellular processes associated with CLSPN-mediated functions.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag GST
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Accession
Q9HCP0-1 (D2-K422)
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Gene ID53944
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Protein Length
Full Length of Isoform-1
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Synonyms
CSNK1G1; Non-Specific Serine/Threonine Protein Kinase; Casein Kinase 1 Gamma 1; Casein Kinase 1, Gamma 1; CK1gamma1; CKI-Gamma 1; Casein Kinase I Isoform Gamma-1
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AA Sequence
DHPSREKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTHRDRPSQQQPLRNQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKCCCFFKRKRKKTAQRHK
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Purity
≥ 80%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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