1. Recombinant Proteins
  2. Others
  3. ELAVL3 Protein, Human (P.pastoris, His)

ELAVL3 Protein, Human (P.pastoris, His)

Cat. No.: HY-P71819
Handling Instructions

ELAVL3 protein is an RNA-binding protein that specifically binds to the ARE sequence in target mRNA, including VEGF. It may also interact with polyA tracts through its RRM3. ELAVL3 Protein, Human (P.pastoris, His) is the recombinant human-derived ELAVL3 protein, expressed by P. pastoris , with N-His labeled tag. The total length of ELAVL3 Protein, Human (P.pastoris, His) is 367 a.a., with molecular weight of ~41.5 kDa.

For research use only. We do not sell to patients.

Protein Expression Service

Size Stock
50 μg   Get quote  
100 μg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

ELAVL3 protein is an RNA-binding protein that specifically binds to the ARE sequence in target mRNA, including VEGF. It may also interact with polyA tracts through its RRM3. ELAVL3 Protein, Human (P.pastoris, His) is the recombinant human-derived ELAVL3 protein, expressed by P. pastoris , with N-His labeled tag. The total length of ELAVL3 Protein, Human (P.pastoris, His) is 367 a.a., with molecular weight of ~41.5 kDa.

Background

The ELAVL3 protein serves as an RNA-binding protein, specifically binding to AU-rich element (ARE) sequences within target mRNAs, including VEGF mRNA. Additionally, it may interact with poly-A tracts through its third RNA recognition motif (RRM3). ELAVL3 is implicated in potential roles in neuronal differentiation and maintenance, suggesting its involvement in fundamental processes within the nervous system. Furthermore, it plays a role in the stabilization of GAP43 mRNA and contributes to spatial learning. The protein's functional repertoire extends to interaction with MAP1B light chain LC1, further underscoring its involvement in intricate molecular networks associated with RNA regulation and cellular processes related to neuronal functions and learning.

Species

Human

Source

P. pastoris

Tag

N-His

Accession

Q14576 (1M-367A)

Gene ID
Molecular Construction
N-term
His
ELAVL3 (1M-367A)
Accession # Q14576
C-term
Synonyms
ELAV like 3; ELAV like 4; ELAV like neuron specific RNA binding protein 3; ELAV like neuron specific RNA binding protein 4; ELAV like protein 3; ELAV like protein 4; ELAV-like protein 3; PLE21; PNEM
AA Sequence

MVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSLIARFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA

Molecular Weight

Approximately 41.5 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

ELAVL3 Protein, Human (P.pastoris, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
ELAVL3 Protein, Human (P.pastoris, His)
Cat. No.:
HY-P71819
Quantity:
MCE Japan Authorized Agent: