ELAVL3 Protein, Human (P.pastoris, His)
ELAVL3 protein is an RNA-binding protein that specifically binds to the ARE sequence in target mRNA, including VEGF. It may also interact with polyA tracts through its RRM3. ELAVL3 Protein, Human (P.pastoris, His) is the recombinant human-derived ELAVL3 protein, expressed by P. pastoris , with N-His labeled tag.
- Species: Human
- Source: P. pastoris
-
Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Technical Parameters
-
Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
ELAVL3 protein is an RNA-binding protein that specifically binds to the ARE sequence in target mRNA, including VEGF. It may also interact with polyA tracts through its RRM3. ELAVL3 Protein, Human (P.pastoris, His) is the recombinant human-derived ELAVL3 protein, expressed by P. pastoris , with N-His labeled tag.
Background
The ELAVL3 protein serves as an RNA-binding protein, specifically binding to AU-rich element (ARE) sequences within target mRNAs, including VEGF mRNA. Additionally, it may interact with poly-A tracts through its third RNA recognition motif (RRM3). ELAVL3 is implicated in potential roles in neuronal differentiation and maintenance, suggesting its involvement in fundamental processes within the nervous system. Furthermore, it plays a role in the stabilization of GAP43 mRNA and contributes to spatial learning. The protein's functional repertoire extends to interaction with MAP1B light chain LC1, further underscoring its involvement in intricate molecular networks associated with RNA regulation and cellular processes related to neuronal functions and learning.
Technical Parameters
-
Species Human
-
Source P. pastoris
-
Tag N-His
-
Accession
Q14576 (M1-A367)
-
Molecular Construction
-
N-term
-
His
-
ELAVL3 (M1-A367)
Accession # Q14576 -
C-term
-
-
Protein Length
Full Length
-
Synonyms
ELAVL3; ELAV Like Neuron-Specific RNA Binding Protein 3; ELAV Like RNA Binding Protein 3; DKFZp547J036; PLE21; Hu Antigen C; HUC; Hu-Antigen C; Paraneoplastic Cerebellar Degeneration-Associated Antigen; MGC20653; Paraneoplastic Limbic Encephalitis Antigen
-
AA Sequence
MVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSLIARFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA
-
Predicted Molecular Mass
41.5 kDa
-
Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz
