GLXR Protein, Mouse (His-SUMO)
GLXR is a multifunctional enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase activities. It promotes the conversion of hydroxypyruvic acid into D-glyceric acid, glyoxylic acid into glycolic acid, and oxidation of D-glyceric acid into hydroxypyruvic acid. GLXR Protein, Mouse (His-SUMO) is the recombinant mouse-derived GLXR protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
- Species: Mouse
- Source: E. coli
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
GLXR is a multifunctional enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase activities. It promotes the conversion of hydroxypyruvic acid into D-glyceric acid, glyoxylic acid into glycolic acid, and oxidation of D-glyceric acid into hydroxypyruvic acid. GLXR Protein, Mouse (His-SUMO) is the recombinant mouse-derived GLXR protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
Background
The GLXR protein, characterized by its multifunctional enzymatic activities, acts as a hydroxy-pyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase. Its versatile enzymatic functions involve the reduction of hydroxypyruvate to D-glycerate and glyoxylate to glycolate, while also oxidizing D-glycerate to hydroxypyruvate. This dynamic enzymatic profile suggests a pivotal role for GLXR in the interconversion of key metabolites within cellular pathways. The ability of GLXR to catalyze these reactions reflects its importance in metabolic processes where hydroxy-pyruvate, glyoxylate, and D-glycerate are involved, emphasizing its significance in maintaining metabolic homeostasis (
Technical Parameters
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Species Mouse
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Source E. coli
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Tag N-6*His;N-SUMO
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Accession
Q91Z53 (M1-L328)
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Molecular Construction
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N-term
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6*His-SUMO
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GLXR (M1-L328)
Accession # Q91Z53 -
C-term
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Protein Length
Full Length
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Synonyms
GRHPR; PH2; Prev. GLXR; Epididymis Secretory Sperm Binding Protein; Prev. GLYD; Primary Hyperoxaluria Type 2; Glyoxylate Reductase/Hydroxypyruvate Reductase; Glycerate-2-Dehydrogenase; Glyoxylate And Hydroxypyruvate Reductase; Glyoxylate Reductase And Hyd
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AA Sequence
MKPARLMKVFVTGPLPAEGRAALAQAADCEVEQWNSDDPIPRKDLEQGVVGAHGLLCRLSDRVDKKLLDAAGANLRVISTLSVGVDHLALDEIKKRGIRVGYTPGVLTDATAELAVSLLLTTCRRLPEAIEEVKNGGWSSWSPLWMCGYGLSQSTVGIVGLGRIGQAIARRLKPFGVQRFLYTGRQPRPQEAAEFQAEFVPIAQLAAESDFIVVSCSLTPDTMGLCSKDFFQKMKNTAIFINISRGDVVNQEDLYQALASGQIAAAGLDVTTPEPLPPSHPLLTLKNCVILPHIGSATYKTRNTMSLLAANNLLAGLRGEAMPSELKL
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Predicted Molecular Mass
51.3 kDa
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US;may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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