GUCY2C/Guanylyl cyclase C Protein, Mouse (CHO, His)
GUCY2C, a vital guanylyl cyclase, catalyzes the synthesis of cyclic cGMP from GTP. GUCY2C/Guanylyl cyclase C Protein, Mouse (CHO, His) is the recombinant mouse-derived GUCY2C/Guanylyl cyclase C protein, expressed by CHO, with C-His labeled tag.
- Species: Mouse
- Source: CHO
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
GUCY2C, a vital guanylyl cyclase, catalyzes the synthesis of cyclic cGMP from GTP. GUCY2C/Guanylyl cyclase C Protein, Mouse (CHO, His) is the recombinant mouse-derived GUCY2C/Guanylyl cyclase C protein, expressed by CHO, with C-His labeled tag.
Background
GUCY2C, a guanylyl cyclase, plays a crucial role in catalyzing the synthesis of cyclic (cGMP) from GTP.
Technical Parameters
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Species Mouse
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Source CHO
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Tag C-His
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Accession
Q3UWA6-1 (V20-M433)
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Gene ID14917
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Molecular Construction
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N-term
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GUCY2C (V20-M433)
Accession # Q3UWA6-1 -
His
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C-term
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Protein Length
Extracellular Domain
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Synonyms
GUCY2C; Heat-Stable Enterotoxin Receptor; Prev. GUC2C; Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor); STAR; Heat Stable Enterotoxin Receptor; GC-C; Alternative Protein GUCY2C; Guanylyl Cyclase C; DIAR6; STA Receptor; MECIL; HSER; MUCIL; GCC; HST
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AA Sequence
VFWASQVRQNCRNGSYEISVLMMDNSAYKEPMQNLREAVEEGLDIVRKRLREADLNVTVNATFIYSDGLIHKSGDCRSSTCEGLDLLREITRDHKMGCALMGPSCTYSTFQMYLDTELNYPMISAGSYGLSCDYKETLTRILPPARKLMYFLVDFWKVNNASFKPFSWNSSYVYKNGSEPEDCFWYLNALEAGVSYFSEVLNFKDVLRRSEQFQEILTGHNRKSNVIVMCGTPESFYDVKGDLQVAEDTVVILVDLFSNHYFEENTTAPEYMDNVLVLTLPSEQSTSNTSVAERFSSGRSDFSLAYLEGTLLFGHMLQTFLENGENVTGPKFARAFRNLTFQGFAGPVTLDDSGDIDNIMSLLYVSLDTRKYKVLMKYDTHKNKTIPVAENPNFIWKNHKLPNDVPGLGPQILM
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Predicted Molecular Mass
49 kDa
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Molecular Weight
Approximately 80-100 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Glycosylation
Yes
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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