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hmgn1-protein-human

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Compare Product Name Species Source
  • HY-P75810
    HMGN3 Protein, Human (His)

    High mobility group nucleosome-binding domain-containing protein 3; TRIP-7; hmgn3

    		 Human E. coli
    HMGN3, binding to nucleosomes, regulates chromatin structure, impacting chromatin-dependent processes like transcription and DNA repair. It influences insulin and glucagon levels, modulating pancreatic gene expression related to insulin secretion. HMGN3 specifically binds to the promoter region of the glucose transporter SLC2A2, recruiting PDX1 and other transcription factors. It also regulates the expression of SLC6A9, a glycine transporter in the central nervous system. Additionally, HMGN3 may play a role in ocular development and astrocyte function. HMGN3 Protein, Human (His) is the recombinant human-derived HMGN3 protein, expressed by E. coli , with N-His labeled tag. The total length of HMGN3 Protein, Human (His) is 77 a.a., with molecular weight of ~16 kDa.

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