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HNRNPA2B1 Protein, Human (GST)

Cat. No.: HY-P72231
Handling Instructions

Heterogeneous nuclear ribonucleoproteins A2/B1 is an important RNA-binding protein that affects the RNA processing, splicing, transport and stability of many genes. Heterogeneous nuclear ribonucleoproteins A2/B1 is expressed during proliferation and metastasis of various cancer types and promotes such processes. HNRNPA2B1 Protein, Human (GST) is the recombinant human-derived HNRNPA2B1 protein, expressed by E. coli , with N-GST labeled tag. The total length of HNRNPA2B1 Protein, Human (GST) is 249 a.a., with molecular weight of ~55.4 kDa.

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Description

Heterogeneous nuclear ribonucleoproteins A2/B1 is an important RNA-binding protein that affects the RNA processing, splicing, transport and stability of many genes. Heterogeneous nuclear ribonucleoproteins A2/B1 is expressed during proliferation and metastasis of various cancer types and promotes such processes. HNRNPA2B1 Protein, Human (GST) is the recombinant human-derived HNRNPA2B1 protein, expressed by E. coli , with N-GST labeled tag. The total length of HNRNPA2B1 Protein, Human (GST) is 249 a.a., with molecular weight of ~55.4 kDa.

Background

Heterogeneous nuclear ribonucleoproteins A2/B1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). Heterogeneous nuclear ribonucleoproteins A2/B1 is RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). Heterogeneous nuclear ribonucleoproteins A2/B1 is associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. Heterogeneous nuclear ribonucleoproteins A2/B1 has distinct nucleic acid binding properties. Heterogeneous nuclear ribonucleoproteins A2/B1 has two repeats of quasi-RRM domains that bind to RNAs. Heterogeneous nuclear ribonucleoproteins A2/B1 has been described to generate two alternatively spliced transcript variants which encode different isoforms[1][2][3][4][5].

Species

Human

Source

E. coli

Tag

N-GST

Accession

I6L957 (M1-Q249)

Gene ID

/

Molecular Construction
N-term
GST
HNRNPA2B1 (M1-Q249)
Accession # I6L957
C-term
Synonyms
Hnrnpa2b1; Hnrpa2b1; Heterogeneous nuclear ribonucleoproteins A2/B1; hnRNP A2/B1
AA Sequence

MEREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEDLEVAILEVAPVMEEEEEDMVVEDLDMATRVGATEVVMTTMEEEIMEVEITMILEIITSNLLTTVQ

Molecular Weight

Approximately 55.4 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

HNRNPA2B1 Protein, Human (GST) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
HNRNPA2B1 Protein, Human (GST)
Cat. No.:
HY-P72231
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