KDM4C Protein, Human (sf9, GST)
KDM4C Protein, Human (sf9, GST) is the recombinant human-derived KDM4C, expressed by Sf9 insect cells , with GST labeled tag. ,
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
KDM4C Protein, Human (sf9, GST) is the recombinant human-derived KDM4C, expressed by Sf9 insect cells , with GST labeled tag. ,
Background
KDM4C is a histone demethylase that specifically targets 'Lys-9' and 'Lys-36' residues of histone H3, playing a central role in histone code regulation. It does not act on H3 'Lys-4', 'Lys-27', or H4 'Lys-20' residues. The enzyme demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residues but shows no activity toward mono- or dimethylated residues. The demethylation reaction produces formaldehyde and succinate. by similar functions also include involvement in chromatin remodeling and gene expression regulation.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag GST
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Accession
Q9H3R0-1 (M1-V460)
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Gene ID23081
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Protein Length
Partial
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Synonyms
KDM4C; Jumonji Domain-Containing Protein 2C; Prev. JMJD2C; Lysine-Specific Demethylase 4C; GASC1; Tudor Domain Containing 14C; KIAA0780; JHDM3C; TDRD14C; [Histone H3]-Trimethyl-L-Lysine(9) Demethylase; JmjC Domain-Containing Histone Demethylation Protein
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AA Sequence
MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWLQRRRKVRKASRSFQCARSTSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAVKLRNTEASSEEESSASRMQVEQNLSDHIKLSGNSCLSTSV
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Molecular Weight
Approximately 82 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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