2. Protéines recombinantes
  3. Enzymes & Regulators
  4. Oxidoreductases (EC 1)
  5. KDM4C Protein, Human (sf9, GST)

KDM4C Protein, Human (sf9, GST) is the recombinant human-derived KDM4C, expressed by Sf9 insect cells , with GST labeled tag. ,

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Description

KDM4C Protein, Human (sf9, GST) is the recombinant human-derived KDM4C, expressed by Sf9 insect cells , with GST labeled tag. ,
Background

KDM4C is a histone demethylase that specifically targets 'Lys-9' and 'Lys-36' residues of histone H3, playing a central role in histone code regulation. It does not act on H3 'Lys-4', 'Lys-27', or H4 'Lys-20' residues. The enzyme demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residues but shows no activity toward mono- or dimethylated residues. The demethylation reaction produces formaldehyde and succinate. by similar functions also include involvement in chromatin remodeling and gene expression regulation.
Species

Human
Source

Sf9 insect cells
Tag

GST
Accession

Q9H3R0-1 (M1-V460)
Gene ID

23081
Protein Length

Partial
Synonyms
GASC1; JHDM3C; JMJD2C; KIAA0780
AA Sequence

MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWLQRRRKVRKASRSFQCARSTSKRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEKSEAAVKLRNTEASSEEESSASRMQVEQNLSDHIKLSGNSCLSTSV

Predicted Molecular Mass
82 kDa
Pureté

≥ 95%, as determined by reducing SDS-PAGE.
Documentation
Instruction de manipulation (2659 KB)

KDM4C Protein, Human (sf9, GST) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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KDM4C Protein, Human (sf9, GST)
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