MYO3A Protein, Human (Active, sf9, His, GST, Strep)
MYO3A Protein, Human (Active, sf9, His, GST, Strep) is the recombinant human-derived MYO3A, expressed by sf9 insect cells , with Strep, His, GST labeled tag. ,
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
MYO3A Protein, Human (Active, sf9, His, GST, Strep) is the recombinant human-derived MYO3A, expressed by sf9 insect cells , with Strep, His, GST labeled tag. ,
Background
MYO3A is an actin-dependent motor protein with protein kinase activity, playing a crucial role in hearing. It likely also contributes to vision and is essential for normal cochlear hair bundle development and auditory function. This protein is involved in the early stages of cochlear hair bundle morphogenesis, influencing the number and length of stereocilia while restricting microvilli growth within developing auditory hair bundles, thereby shaping their staircase-like architecture. Additionally, MYO3A facilitates actin elongation at stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments. by similar: Its functions are closely tied to actin dynamics and the precise structural regulation of auditory hair bundles.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag Strep;His;GST
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Accession
Q8NEV4-1 (M1-G434)
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Gene ID53904
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Protein Length
Partial
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Synonyms
MYO3A; Epididymis Secretory Sperm Binding Protein; Prev. DFNB30; MYO3A Protein; Myosin-IIIa; DFNA90; Myosin IIIA; Deafness, Autosomal Recessive 30
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AA Sequence
MFPLIGKTIIFDNFPDPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRHRRNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLADLHPMRALFKIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSELLQHKFITQIEGKDVMLQKQLTEFIGIHQCMGGTEKARRERIHTKKGNFNRPLISNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSKRTASPPHIFAMADLGYQSMITYNSDQCIVISGESG
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Predicted Molecular Mass
77.8 kDa
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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