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NGL-1/LRRC4C Protein, Mouse (HEK293, His)

Cat. No.: HY-P77103
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NGL-1/LRRC4C protein promotes neurite outgrowth in thalamic neurons, shaping neural circuit architecture. It interacts with NTNG1 and WHRN to modulate neurite outgrowth and synaptic connections. Investigating its mechanisms and downstream effects could provide insights into its role in neural development and circuit formation. NGL-1/LRRC4C Protein, Mouse (HEK293, His) is the recombinant mouse-derived NGL-1/LRRC4C protein, expressed by HEK293 , with C-His labeled tag. The total length of NGL-1/LRRC4C Protein, Mouse (HEK293, His) is 527 a.a., with molecular weight of ~55.5 KDa.

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Description

NGL-1/LRRC4C protein promotes neurite outgrowth in thalamic neurons, shaping neural circuit architecture. It interacts with NTNG1 and WHRN to modulate neurite outgrowth and synaptic connections. Investigating its mechanisms and downstream effects could provide insights into its role in neural development and circuit formation. NGL-1/LRRC4C Protein, Mouse (HEK293, His) is the recombinant mouse-derived NGL-1/LRRC4C protein, expressed by HEK293 , with C-His labeled tag. The total length of NGL-1/LRRC4C Protein, Mouse (HEK293, His) is 527 a.a., with molecular weight of ~55.5 KDa.

Background

The NGL-1/LRRC4C protein appears to play a role in promoting neurite outgrowth in developing thalamic neurons, suggesting its involvement in the intricate processes of neuronal growth and connectivity. Its potential to facilitate the extension of neurites implies a key function in shaping the architecture of neural circuits. Additionally, NGL-1/LRRC4C interacts with NTNG1 and WHRN, indicating its participation in molecular interactions that could further modulate neurite outgrowth and influence the development of synaptic connections. Further exploration into the specific mechanisms and downstream effects of NGL-1/LRRC4C in promoting neurite outgrowth and its interactions with NTNG1 and WHRN could provide valuable insights into its role in neural development and circuit formation.

Species

Mouse

Source

HEK293

Tag

C-His

Accession

Q8C031 (M1-K527)

Gene ID

241568  [NCBI]

Molecular Construction
N-term
LRRC4C (M1-K527)
Accession # Q8C031
His
C-term
Synonyms
Leucine-rich repeat-containing protein 4C; Netrin-G1 ligand; KIAA1580; NGL1
Molecular Weight

Approximately 55.5 kDa.

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

NGL-1/LRRC4C Protein, Mouse (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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NGL-1/LRRC4C Protein, Mouse (HEK293, His)
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HY-P77103
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