NR6A1 Protein, Human
NR6A1 Protein, Human is the recombinant human-derived NR6A1, expressed by E. coli , with tag Free labeled tag. ,
- Species: Human
- Source: E. coli
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
NR6A1 Protein, Human is the recombinant human-derived NR6A1, expressed by E. coli , with tag Free labeled tag. ,
NR6A1 is an orphan nuclear receptor that binds to a response element containing the sequence 5'-TCAAGGTCA-3'. It acts as a regulator of embryonic stem cell pluripotency by mediating repression of POU5F1/OCT4: binding to the DR0 element within the POU5F1/OCT4 promoter and inhibiting POU5F1/OCT4 expression during embryonic stem cell differentiation. Additionally, it is involved in the regulation of gene expression in germ cell development during gametogenesis (by similar).
Technical Parameters
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Species Human
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Source E. coli
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Tag Tag Free
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Accession
Q15406 (E2-E480)
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Gene ID2649
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Protein Length
Partial
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Synonyms
NR6A1; Germ Cell Nuclear Factor; Prev. GCNF; HRTR; RTR; Retinoic Acid Receptor-Related Testis-Associated Receptor; Retinoid Receptor-Related Testis-Specific Receptor; Nuclear Receptor Subfamily 6, Group A, Member 1; GCNF1; NR61; CT150; Nuclear Receptor Su
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AA Sequence
ERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGTISVSDDRAEQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSPGNRASESNQPSPGSTLSSSRSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLPQQARSLDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE
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Predicted Molecular Mass
54.4 kDa
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Purity
≥ 85%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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