1. Recombinant Proteins
  2. Viral Proteins
  3. SARS-CoV Proteins
  4. Nucleocapsid Protein (His)

Nucleocapsid Protein (His)

Cat. No.: HY-P7437
Handling Instructions

Nucleocapsid Protein (His) expressed by E. coli systems. Nucleocapsid Protein is required for coronavirus RNA synthesis and has RNA chaperone activity[1].

For research use only. We do not sell to patients.

Protein Expression Service

Recombinant Proteins-MedChemExpress
Size Price Stock Quantity
10 μg $55 In-stock
Estimated Time of Arrival: December 31
50 μg $165 In-stock
Estimated Time of Arrival: December 31
1 mg $720 Get quote

* Please select Quantity before adding items.

Nucleocapsid Protein (His) Related Classifications

  • Technical Parameters

  • Properties

  • Documentation




E. coli



Gene ID


2019-nCoV coronavirus NP Protein; 2019-nCoV np Protein; 2019-nCoV novel coronavirus Nucleoprotein Protein
AA Sequence


Molecular Weight

50-60 kDa

Biological Activity
Data is not available.



Supplied as a 0.2 μm filter solution of 20 mM Tris-HCl, 300 mM NaCl, 10% Glycerol, 1 mM EDTA, pH 8.0.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Storage & Stability

Stored at -80°C. It is stable at -20℃ for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.


Shipping with dry ice.


Coronaviruses are enveloped viruses with a positive-sense RNA genomeand and has a nucleocapsid of helical symmetry. The Nucleocapsid Protein localize to the cytoplasm and the nucleolus in both virus-infected primary cells and in cells transfected with plasmids that express N protein[1].
Nucleocapsid Protein is a basic protein and is abundant in coronaviruses, which has nonspecific binding activity toward nucleic acids, including ssRNA, ssDNA, and dsDNA. Nucleocapsid Protein is an essential RNA-binding viral protein in human coronavirus (CoV)-infected cells, is required for the replication and transcription of viral RNA. Human CoV NP is a valid target for antiviral drug research[1][2].

  • Reconstitution Calculator

  • Dilution Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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