ODC1 Protein, Human (His-SUMO, Myc)
ODC (ornithine decarboxylase) is the rate-limiting enzyme in polyamine biosynthesis, catalyzing the conversion of ornithine to putrescine, a precursor of polyamines such as spermidine and spermine, which influence cell proliferation and various cellular processes. ODC1 Protein, Human (His-SUMO, Myc) is the recombinant human-derived ODC1, expressed by E. coli, with N-10*His, C-Myc, N-SUMO labeled tag.
- Species: Human
- Source: E. coli
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
ODC (ornithine decarboxylase) is the rate-limiting enzyme in polyamine biosynthesis, catalyzing the conversion of ornithine to putrescine, a precursor of polyamines such as spermidine and spermine, which influence cell proliferation and various cellular processes. ODC1 Protein, Human (His-SUMO, Myc) is the recombinant human-derived ODC1, expressed by E. coli, with N-10*His, C-Myc, N-SUMO labeled tag.
Background
ODC (Ornithine Decarboxylase) is the rate-limiting enzyme in polyamine biosynthesis, and its activity is regulated by specific inhibitors, AZs (Antiaminoacidases), which in turn are inhibited by AZI (Antiaminoacidase Inhibitors). ODC1 catalyzes the first and rate-limiting step in polyamine biosynthesis, converting ornithine to putrescine, a precursor of polyamines such as spermidine and spermine. Polyamines are essential for cell proliferation and are involved in a variety of cellular processes ranging from DNA replication to apoptosis.
Technical Parameters
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Species Human
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Source E. coli
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Tag N-10*His;C-Myc;N-SUMO
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Accession
P11926 (M1-V461)
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Gene ID4953
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Protein Length
Full Length
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Synonyms
ODC1; Alternative Protein ODC1; Ornithine Decarboxylase 1; NEDBIA; ODC; NEDBA; Ornithine Decarboxylase; BABS
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AA Sequence
MNNFGNEEFDCHFLDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSKAIVKTLAATGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQIKYAANNGVQMMTFDSEVELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLRTSRLLLERAKELNIDVVGVSFHVGSGCTDPETFVQAISDARCVFDMGAEVGFSMYLLDIGGGFPGSEDVKLKFEEITGVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKIVLKEQTGSDDEDESSEQTFMYYVNDGVYGSFNCILYDHAHVKPLLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCDLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPTIYYVMSGPAWQLMQQFQNPDFPPEVEEQDASTLPVSCAWESGMKRHRAACASASINV
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Predicted Molecular Mass
71.1 kDa
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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