ODC1 Protein, Human (His-SUMO, Myc)

ODC (ornithine decarboxylase) is the rate-limiting enzyme in polyamine biosynthesis, catalyzing the conversion of ornithine to putrescine, a precursor of polyamines such as spermidine and spermine, which influence cell proliferation and various cellular processes. ODC1 Protein, Human (His-SUMO, Myc) is the recombinant human-derived ODC1, expressed by E. coli, with N-10*His, C-Myc, N-SUMO labeled tag.

ODC (Ornithine Decarboxylase) is the rate-limiting enzyme in polyamine biosynthesis, and its activity is regulated by specific inhibitors, AZs (Antiaminoacidases), which in turn are inhibited by AZI (Antiaminoacidase Inhibitors). ODC1 catalyzes the first and rate-limiting step in polyamine biosynthesis, converting ornithine to putrescine, a precursor of polyamines such as spermidine and spermine. Polyamines are essential for cell proliferation and are involved in a variety of cellular processes ranging from DNA replication to apoptosis.

Human

E. coli

N-10*His;C-Myc;N-SUMO

P11926 (M1-V461)

4953

Full Length

MNNFGNEEFDCHFLDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSKAIVKTLAATGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQIKYAANNGVQMMTFDSEVELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLRTSRLLLERAKELNIDVVGVSFHVGSGCTDPETFVQAISDARCVFDMGAEVGFSMYLLDIGGGFPGSEDVKLKFEEITGVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKIVLKEQTGSDDEDESSEQTFMYYVNDGVYGSFNCILYDHAHVKPLLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCDLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPTIYYVMSGPAWQLMQQFQNPDFPPEVEEQDASTLPVSCAWESGMKRHRAACASASINV

≥ 90%, as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.