PDILT Protein, Human (HEK293, His)
The PDILT protein is a possible redox-inactive chaperone essential in spermatogenesis, forming non-disulfide-linked homodimers. Its role emphasizes its importance in male germ cell development. PDILT Protein, Human (HEK293, His) is the recombinant human-derived PDILT protein, expressed by HEK293 , with C-6*His labeled tag.
- Species: Human
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
The PDILT protein is a possible redox-inactive chaperone essential in spermatogenesis, forming non-disulfide-linked homodimers. Its role emphasizes its importance in male germ cell development. PDILT Protein, Human (HEK293, His) is the recombinant human-derived PDILT protein, expressed by HEK293 , with C-6*His labeled tag.
Background
The PDILT protein is identified as a probable redox-inactive chaperone with involvement in spermatogenesis. Existing as a homodimer, this chaperone does not form disulfide linkages within the dimeric structure. Its role in spermatogenesis underscores its significance in the intricate processes associated with male germ cell development. Furthermore, PDILT interacts with ERO1A and CLGN, indicating potential associations with proteins involved in redox regulation and chaperone activities. A deeper exploration of the specific molecular mechanisms and functional implications of PDILT in spermatogenesis and its interactions with ERO1A and CLGN will contribute to a comprehensive understanding of its role in male reproductive biology.
Technical Parameters
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Species Human
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Source HEK293
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Tag C-6*His
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Accession
Q8N807 (S21-L584)
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Gene ID204474 [NCBI]
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Molecular Construction
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N-term
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PDILT (S21-L584)
Accession # Q8N807 -
6*His
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C-term
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Protein Length
Full Length of Mature Protein
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Synonyms
PDILT; Protein Disulfide Isomerase Family A, Member 7; Protein Disulfide Isomerase Like, Testis Expressed; Protein Disulfide Isomerase-Like Protein Of The Testis; PDIA7; Protein Disulfide Isomerase-Like, Testis Expressed; Protein Disulfide-Isomerase-Like
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AA Sequence
SPEVNAGVSSIHITKPVHILEERSLLVLTPAGLTQMLNQTRFLMVLFHNPSSKQSRNLAEELGKAVEIMGKGKNGIGFGKVDITIEKELQQEFGITKAPELKLFFEGNRSEPISCKGVVESAALVVWLRRQISQKAFLFNSSEQVAEFVISRPLVIVGFFQDLEEEVAELFYDVIKDFPELTFGVITIGNVIGRFHVTLDSVLVFKKGKIVNRQKLINDSTNKQELNRVIKQHLTDFVIEYNTENKDLISELHIMSHMLLFVSKSSESYGIIIQHYKLASKEFQNKILFILVDADEPRNGRVFKYFRVTEVDIPSVQILNLSSDARYKMPSDDITYESLKKFGRSFLSKNATKHQSSEEIPKYWDQGLVKQLVGKNFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDVTANDIQLMYLDRYPFFRLFPSGSQQAVLYKGEHTLKGFSDFLESHIKTKIEDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELENMTKYVSKLEEPAGKKKTSEEVVVVVAKPKGPPVQKKKPKVKEEL
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Predicted Molecular Mass
65.5 kDa
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Molecular Weight
Approximately 92 kDa, based on SDS-PAGE under reducing conditions.
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Glycosylation
Yes
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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