PI4K2B Protein, Human (sf9, His, GST)
PI4K2B Protein, Human (sf9, His, GST) is the recombinant human-derived PI4K2B, expressed by sf9 insect cells , with His, GST labeled tag. ,
- Species: Human
- Source: Sf9 insect cells
-
Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Technical Parameters
-
Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
PI4K2B Protein, Human (sf9, His, GST) is the recombinant human-derived PI4K2B, expressed by sf9 insect cells , with His, GST labeled tag. ,
Background
PI4K2B collaborates with PI4K2A and type III PI4Ks (PIK4CA and PIK4CB) to contribute to cellular PI4-kinase activity (by similar: PubMed:11923287, PubMed:12324459). Its role is particularly prominent in plasma membrane, endosomal, and Golgi compartments (by similar: PubMed:11923287, PubMed:12324459). The enzyme phosphorylates phosphatidylinositol (PI) to PI4P, initiating the production of phosphatidylinositol 4,5-bisphosphate (PIP2) – a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3) (by similar: PubMed:11923287, PubMed:12324459). PI4K2B enhances InsP3 generation in stimulated cells and is implicated in vesicular trafficking regulation.
Technical Parameters
-
Species Human
-
Source Sf9 insect cells
-
Tag His;GST
-
Accession
Q8TCG2 (E2-W481)
-
Gene ID55300
-
Protein Length
Full Length
-
Synonyms
PI4K2B; PI4KII-BETA; Phosphatidylinositol 4-Kinase Type 2 Beta; FLJ11105; PI4KIIB; Phosphatidylinositol 4-Kinase Type-II Beta; PIK42B; Phosphatidylinositol 4-Kinase Type II-Beta; Phosphatidylinositol 4-Kinase Type 2-Beta; Phosphatidylinositol 4-Kinase Typ
-
AA Sequence
EDPSEPDRLASADGGSPEEEEDGEREPLLPRIAWAHPRRGAPGSAVRLLDAAGEEGEAGDEELPLPPGDVGVSRSSSAELDRSRPAVSVTIGTSEMNAFLDDPEFADIMLRAEQAIEVGIFPERISQGSSGSYFVKDPKRKIIGVFKPKSEEPYGQLNPKWTKYVHKVCCPCCFGRGCLIPNQGYLSEAGAYLVDNKLHLSIVPKTKVVWLVSETFNYNAIDRAKSRGKKYALEKVPKVGRKFHRIGLPPKIGSFQLFVEGYKEAEYWLRKFEADPLPENIRKQFQSQFERLVILDYIIRNTDRGNDNWLVRYEKQKCEKEIDHKESKWIDDEEFLIKIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVPFSEEIRNLILPYISDMNFVQDLCEDLYELFKTDKGFDKATFESQMSVMRGQILNLTQALRDGKSPFQLVQIPCVIVERSQGGSQGRIVHLSNSFTQTVNCRKPFFSSW
-
Predicted Molecular Mass
82.4 kDa
-
Purity
≥ 80%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz
