PIK3IP1 Protein, Mouse (HEK293, His)
Based on 1 Customer Validation
The PIK3IP1 protein binds to the catalytic subunit of phosphatidylinositol 3-kinase. It negatively regulates phosphatidylinositol 3-kinase activity and signaling. PIK3IP1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PIK3IP1 protein, expressed by HEK293 , with C-His labeled tag.
- Species: Mouse
- Source: HEK293
-
Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Technical Parameters
-
Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
The PIK3IP1 protein binds to the catalytic subunit of phosphatidylinositol 3-kinase. It negatively regulates phosphatidylinositol 3-kinase activity and signaling. PIK3IP1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PIK3IP1 protein, expressed by HEK293 , with C-His labeled tag.
Background
The PIK3IP1 protein is predicted to possess phosphatidylinositol 3-kinase catalytic subunit binding activity. It plays a role in the negative regulation of phosphatidylinositol 3-kinase activity and phosphatidylinositol 3-kinase signaling. This protein is predicted to be located in the plasma membrane and serves as an integral component of the membrane. It is expressed in various structures, including the brain meninges, genitourinary system, heart, lung, and oral epithelium. It is orthologous to human PIK3IP1 (phosphoinositide-3-kinase interacting protein 1). In terms of expression, it has broad expression in thymus adult, testis adult, and 24 other tissues.
MCE Validation Data
-
Purity - SDS-PAGE
Purity - SDS-PAGE
Technical Parameters
-
Species Mouse
-
Source HEK293
-
Tag C-His
-
Accession
Q7TMJ8-1/NP_835362.2 (S22-L170)
-
Molecular Construction
-
N-term
-
PIK3IP1 (S22-L170)
Accession # Q7TMJ8-1/NP_835362.2 -
His
-
C-term
-
-
Protein Length
Extracellular Domain
-
Synonyms
PIK3IP1; TrIP; Phosphoinositide-3-Kinase Interacting Protein 1; Transmembrane Inhibitor Of PI3K; HGFL; PI3K-Interacting Protein 1; Phosphoinositide-3-Kinase-Interacting Protein 1; MGC17330; Kringle Domain-Containing Protein HGFL; HHGFL(S)
-
AA Sequence
SGGCFWDNGHLYREDQPSPAPGLRCLNWLAAQGSRESLTEPSPGNHNYCRNPDQDPRGPWCYISSETGVPEKRPCEDVSCPETTSQAPPPSSAMELEEKSGAPGDKEAQVFPPANALPARSEAAEVQPVIGISQLVRMNSKEKKDLGTL
-
Molecular Weight
Approximately 23 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
-
Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
-
Data Sheet (236 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz
