PIK3IP1 Protein, Mouse (HEK293, His)

The PIK3IP1 protein binds to the catalytic subunit of phosphatidylinositol 3-kinase. It negatively regulates phosphatidylinositol 3-kinase activity and signaling. PIK3IP1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PIK3IP1 protein, expressed by HEK293 , with C-His labeled tag.

The PIK3IP1 protein is predicted to possess phosphatidylinositol 3-kinase catalytic subunit binding activity. It plays a role in the negative regulation of phosphatidylinositol 3-kinase activity and phosphatidylinositol 3-kinase signaling. This protein is predicted to be located in the plasma membrane and serves as an integral component of the membrane. It is expressed in various structures, including the brain meninges, genitourinary system, heart, lung, and oral epithelium. It is orthologous to human PIK3IP1 (phosphoinositide-3-kinase interacting protein 1). In terms of expression, it has broad expression in thymus adult, testis adult, and 24 other tissues.

Mouse

HEK293

C-His

Q7TMJ8-1/NP_835362.2 (S22-L170)

216505  [NCBI]

Extracellular Domain

SGGCFWDNGHLYREDQPSPAPGLRCLNWLAAQGSRESLTEPSPGNHNYCRNPDQDPRGPWCYISSETGVPEKRPCEDVSCPETTSQAPPPSSAMELEEKSGAPGDKEAQVFPPANALPARSEAAEVQPVIGISQLVRMNSKEKKDLGTL

Approximately 23 kDa.

• 
  ≥ 95%, as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.